ND-322 hydrochloride
Based on 1 Customer Validation
ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.14%
- CAS. Nr.: 1333379-23-9
- Formel: C15H16ClNO3S2
- Molecular Weight:357.88
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Speicherung:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Chemical Information
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CAS. Nr. 1333379-23-9
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Appearance Solid
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Molecular Weight 357.88
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Formel C15H16ClNO3S2
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Color Light yellow to yellow
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SMILES
NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(CC3SC3)=O.Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (279.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Gooyit M, et, al. Selective water-soluble gelatinase inhibitor prodrugs. J Med Chem. 2011 Oct 13;54(19):6676-90. [Content Brief]
[2]. Marusak C, et, al. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacol Res. 2016 Nov;113(Pt A):515-520. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7942 mL | 13.9712 mL | 27.9423 mL | 69.8558 mL |
| 5 mM | 0.5588 mL | 2.7942 mL | 5.5885 mL | 13.9712 mL | |
| 10 mM | 0.2794 mL | 1.3971 mL | 2.7942 mL | 6.9856 mL | |
| 15 mM | 0.1863 mL | 0.9314 mL | 1.8628 mL | 4.6571 mL | |
| 20 mM | 0.1397 mL | 0.6986 mL | 1.3971 mL | 3.4928 mL | |
| 25 mM | 0.1118 mL | 0.5588 mL | 1.1177 mL | 2.7942 mL | |
| 30 mM | 0.0931 mL | 0.4657 mL | 0.9314 mL | 2.3285 mL | |
| 40 mM | 0.0699 mL | 0.3493 mL | 0.6986 mL | 1.7464 mL | |
| 50 mM | 0.0559 mL | 0.2794 mL | 0.5588 mL | 1.3971 mL | |
| 60 mM | 0.0466 mL | 0.2329 mL | 0.4657 mL | 1.1643 mL | |
| 80 mM | 0.0349 mL | 0.1746 mL | 0.3493 mL | 0.8732 mL | |
| 100 mM | 0.0279 mL | 0.1397 mL | 0.2794 mL | 0.6986 mL |
ND-322 hydrochloride Related Classifications
HY-124939 Related Classifications
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