1333379-23-9
1333379-23-9
Chemical Structure
ND-322 hydrochloride
- CAS No.: 1333379-23-9
- Formula:C15H16ClNO3S2
- Molecular Weight:357.88
IUPAC Name: 4-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)aniline hydrochloride
InChIKey: FOCZQHBXIUOIJR-UHFFFAOYSA-N
SMILES: NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(CC3SC3)=O.Cl
Biological Activity: ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ND-322 hydrochloride | 98.14% | ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination. | ||||||||||||||||||||
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References
- [1]. Gooyit M, et, al. Selective water-soluble gelatinase inhibitor prodrugs. J Med Chem. 2011 Oct 13;54(19):6676-90. [Content Brief]
- [2]. Marusak C, et, al. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacol Res. 2016 Nov;113(Pt A):515-520. [Content Brief]
Keywords
