105 Results for "

human plasma protein

" in MedChemExpress (MCE) Product Catalog:
Products (105)

105 Results for "human plasma protein" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: human serum albumin
HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO -) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.
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4
4 Cited Publications
Cat. No.: HY-13327
CAS No.: 1186486-62-3
Purity:  98.89%
Synonyms: LY2484595
Target:  

CETP

Research Areas:  

Cardiovascular Disease

Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.
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4
4 Cited Publications
Cat. No.: HY-P70700A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STING1; HSTING; Prev. TMEM173; N-Terminal Methionine-Proline-Tyrosine-Serine plasma Membrane Tetraspanner; Transmembrane protein 173; Stimulator Of Interferon Response CGAMP Interactor-DeltaC; STING; Stimulator Of Interferon Response CGAMP Interactor-Delt
Species:  
Human
Source:  
E. coli
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3
3 Cited Publications
Cat. No.: HY-15163
CAS No.: 1204918-72-8
Synonyms: TG02; SB1317
Target:  

JAK CDK FLT3

Research Areas:  

Cancer

Zotiraciclib (TG02; SB1317) is an orally active JAK2/FLT3/CDK2 inhibitor with IC50 values of 13 nM, 73 nM and 56 nM , respectively. Zotiraciclib inhibits cancer cell proliferation, tumor growth and the activity of CYP2D6. Zotiraciclib exhibits high plasma protein binding rate, Caco-2 permeability and tissue distribution capacity, as well as metabolic stability in human and canine liver microsomes. Zotiraciclib achieves tumor growth inhibition in nude mouse models of colon cancer and lymphoma xenografts. Zotiraciclib can be used for research related to colon cancer, B-cell lymphoma, advanced leukemia, acute leukemia and multiple myeloma .
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2
2 Cited Publications
Cat. No.: HY-14950
CAS No.: 211513-37-0
Purity:  99.19%
Synonyms: JTT-705; RO4607381
Target:  

CETP

Research Areas:  

Cardiovascular Disease Cancer

Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
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2
2 Cited Publications
Cat. No.: HY-P70832
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HABP2; Factor VII Activating protein; Hyaluronan Binding protein 2; Hyaluronan-Binding protein 2; HGFAL; FVII Activator; PHBP; PHBSP; FSAP; Hyaluronic Acid Binding protein 2; HABP; plasma Hyaluronan-Binding protein; Hepatocyte Growth Factor Activator-Like
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P70700
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STING1; HSTING; Prev. TMEM173; N-Terminal Methionine-Proline-Tyrosine-Serine plasma Membrane Tetraspanner; Transmembrane protein 173; Stimulator Of Interferon Response CGAMP Interactor-DeltaC; STING; Stimulator Of Interferon Response CGAMP Interactor-Delt
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P1956A
CAS No.: 70024-90-7
Synonyms: human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) (Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO -) in the vascular wall, contributing to the reduction of blood pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
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1
1 Cited Publications
Cat. No.: HY-P99194
CAS No.: 1446419-85-7
Synonyms: REGN1500

Target:  

ANGPTL

Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia .
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1
1 Cited Publications
Cat. No.: HY-P72031
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RBP4; Retinol-Binding protein 4, Interstitial; Retinol Binding protein 4; Retinol-Binding protein 4, plasma; plasma Retinol-Binding protein; Retinol Binding protein 4, plasma; Retinol-Binding protein 4; Retinol-Binding protein; PRBP; MCOPCB10; RBP; RDCCAS
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70231
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: F9; Autoprothrombin IIA; Coagulation Factor IX; Coagulant Factor IX; FIX; Christmas Disease; plasma Thromboplastic Component; Hemophilia B; plasma Thromboplastin Component; Factor IX F9; Christmas Factor; Factor IX; PTC; Factor 9; Truncated Coagulation Fa
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70411
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HYAL1; Hyaluronoglucosaminidase-1; Hyaluronidase 1; Tumor Suppressor LUCA-1; LUCA1; plasma Hyaluronidase; HYAL-1; Hyaluronidase; Hyaluronoglucosaminidase 1; Hyal-1; Lung Carcinoma protein 1; MPS9; Hyaluronidase-1; NAT6; LuCa-1
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P73526
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPING1; Serine (Or Cysteine) proteinase Inhibitor, Clade G (C1 Inhibitor), Member 1, (Angioedema, Hereditary); Prev. C1NH; Serine/Cysteine proteinase Inhibitor Clade G Member 1 Splice Variant 2; plasma Protease C1 Inhibitor; Serine/Cysteine proteinase I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-133668
CAS No.: 2306-33-4
Purity:  96.78%
Monoethyl phthalate is an orally active PDX-1 activator and the major hydrolytic metabolite of Diethyl phthalate (HY-Y0284) in vivo, with reproductive toxicity. Monoethyl phthalate targets aromatase (aromatase/CYP19A1) and PPAR to induce cell proliferation. The plasma protein binding rate of Monoethyl phthalate in rats and humans is lower than that of Diethyl phthalate. It exhibits significant enterohepatic circulation in rats and mainly accumulates in liver tissues. Monoethyl phthalate shows no estrogenic activity in estrogen-dependent human breast cancer cells. Monoethyl phthalate can be used in studies of reproductive toxicity and related environmental endocrine disruption mechanisms .
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Cat. No.: HY-150097
Purity:  ≥99.0%
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .
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Cat. No.: HY-141572
CAS No.: 24529-88-2
Purity:  99.96%
Synonyms: sn-1,2-Dioleoylglycerol; 18:1/18:1-DG
1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm .
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Cat. No.: HY-NP002L
Synonyms: Canine Serum Albumin
CSA Protein (Canine) (Canine Serum Albumin) is a plasma protein derived from dogs. CSA Protein (Canine) exhibits greater flexibility than human serum albumin and bovine serum albumin. Serum albumin is a multifunctional protein with exceptional ligand-binding capacity, which enables it to act as a transport molecule for various metabolites, drugs, nutrients, metals and other molecules .
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Cat. No.: HY-NP002J
CAS No.: 9048-46-8
Horse Serum Albumin is an abundant, multifunctional mammalian plasma protein and transport molecule. Horse Serum Albumin acts as an allergen, exhibits high cross-reactivity with serum albumins from other mammals, and contains epitope regions recognizable by antibodies. Horse Serum Albumin binds a variety of metabolites, drugs, nutrients, metals and other molecules .
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Cat. No.: HY-129035
CAS No.: 2173134-00-2
Purity:  99.92%
Synonyms: Vanin-1-IN-1
Target:  

Pantetheinase

PFI-653 (Vanin-1-IN-1, compound 3), a chemical probe, is a vanin-1 inhibitor that binds to plasma vanin-1 from mouse, rat, dog, and human. Vanin-1 is a cell surface-associated inositol (GPi) -anchored protein that plays important roles in metabolism and inflammation. PFI-653 inhibits vanin-1 from different species with IC50s of 6.85 nM (human recombinant plasma vanin-1), 9.0 nM (human plasma vanin-1), 24.5 nM (mouse recombinant vanin-1), and 53.4 nM (mouse plasma vanin-1) .
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Cat. No.: HY-12089
CAS No.: 262352-17-0
Purity:  99.88%
Synonyms: CP-529414
Target:  

CETP

Research Areas:  

Endocrinology

Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM .
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