SPSB2-iNOS inhibitory cyclic peptide-1
Based on 1 Customer Validation
SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 1621616-13-4
- Formula: C35H56N12O14S2
- Molecular Weight:933.02
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1621616-13-4
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Appearance Solid
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Molecular Weight 933.02
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Formula C35H56N12O14S2
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Color White to off-white
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Sequence
Ac-Cys-Val-Asp-Ile-Asn-Asn-Asn-Cys-NH2 (Disulfide bridge: Cys1-Cys8)
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Sequence Shortening
Ac-CVDINNNC-NH2 (Disulfide bridge: Cys1-Cys8)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (53.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (284 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0718 mL | 5.3589 mL | 10.7179 mL | 26.7947 mL |
| 5 mM | 0.2144 mL | 1.0718 mL | 2.1436 mL | 5.3589 mL | |
| 10 mM | 0.1072 mL | 0.5359 mL | 1.0718 mL | 2.6795 mL | |
| 15 mM | 0.0715 mL | 0.3573 mL | 0.7145 mL | 1.7863 mL | |
| 20 mM | 0.0536 mL | 0.2679 mL | 0.5359 mL | 1.3397 mL | |
| 25 mM | 0.0429 mL | 0.2144 mL | 0.4287 mL | 1.0718 mL | |
| 30 mM | 0.0357 mL | 0.1786 mL | 0.3573 mL | 0.8932 mL | |
| 40 mM | 0.0268 mL | 0.1340 mL | 0.2679 mL | 0.6699 mL | |
| 50 mM | 0.0214 mL | 0.1072 mL | 0.2144 mL | 0.5359 mL |
SPSB2-iNOS inhibitory cyclic peptide-1 Related Classifications
HY-P10383 Related Classifications
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