ANGPTL
Angiopoietin-like protein
Angiopoietin-like proteins (ANGPTLs) are identified as proteins structurally similar to angiopoietins, and the ANGPTL family now consists of eight members. ANGPTLs are secretary proteins, and some ANGPTLs are not only angiogenic factors but also proteins with multiple functions such as glucose metabolism, lipid metabolism, redox regulation and chronic inflammation.
ANGPTL Isoform Specific Products
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ANGPTL Related Products (19)
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ANGPTL Isoform Comparison
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Evinacumab
0 ImagesSynonyms: REGN1500Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia.
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Vupanorsen sodium
0 ImagesSynonyms: IONIS ANGPT-L3Rx sodium; ISIS 703802 sodiumVupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
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Anti-ANGPTL4 Antibody
0 ImagesCat. No.: HY-P990335Anti-ANGPTL4 Antibody is a CHO expressed human antibody targeting ANGPTL4. Anti-ANGPTL4 Antibody has a huIgG1-type heavy chain and a huλ-type light chain with a predicted molecular weight (MW) of 150 kDa. An isotype control for Anti-ANGPTL4 Antibody can be found in Human IgG1 kappa, Isotype Control (HY-P99001).
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Zodasiran
0 ImagesCat. No.: HY-177671CAS No.: 2232918-66-8Synonyms: ARO-ANG3Zodasiran is a siRNA targeted to ANGPTL3 in the liver.
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Pegevongitide
0 ImagesSynonyms: AV-001Pegevongitide is an agonist of the angiopoietin-1 receptor.
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Corveldebart
0 ImagesCorveldebart is a monoclonal antibody of immunoglobulin G1-kappa that targets ANGPTL4. Corveldebart can be used as an immunomodulator.
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Lexosiran
0 ImagesCat. No.: HY-185318CAS No.: 3078403-66-1Lexosiran is a siRNA that inhibits ANGPTL3 (angiopoietin-related protein 3) synthesis, and can be use for the study of antihyperlipidaemic.
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Zodasiran sodium scrambled negative control
0 ImagesCat. No.: HY-177671BZodasiran sodium scrambled negative control is the sequence scrambled negative control of Zodasiran sodium.
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JTE-907
0 ImagesJTE-907 is a selective and orally active cannabinoid CB2 receptor inverse agonist and exerts anti-inflammatory effects. JTE-907 upregulates IL-6, MCP-1, IL-1β, VEGF, ANGPTL4, and TRPV1 in mature adipocytes. JTE-907 downregulates CB1, MCP-1, and IL-1β in preadipocytes. JTE-907 inhibits ear swelling in mice. JTE-907 reverses the protective effects of CB2 agonists and Anandamide (HY-10863) against cytokine-evoked colonic mucosal damage. JTE-907 can be used for the research of allergic dermatitis, obesity, and colitis.
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DC371739
0 ImagesCat. No.: HY-163794CAS No.: 2135765-21-6
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Vupanorsen
0 ImagesCat. No.: HY-153497CAS No.: 2097587-62-5Synonyms: IONIS ANGPT-L3Rx; ISIS 703802Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.
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Zodasiran sodium
0 ImagesCat. No.: HY-177671ACAS No.: 2232918-74-8Synonyms: ARO-ANG3 sodiumZodasiran sodium is a siRNA targeted to ANGPTL3 in the liver.
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Solbinsiran sodium
0 ImagesCat. No.: HY-177666ACAS No.: 2707429-60-3Synonyms: LY3561774 sodiumSolbinsiran sodium is a siRNA targeted to hepatic ANGPTL3.
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Solbinsiran sodium scrambled negative control
0 ImagesCat. No.: HY-177666BSolbinsiran sodium scrambled negative control is the sequence scrambled negative control of Solbinsiran sodium.
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Lexosiran sodium
0 ImagesCat. No.: HY-185318ALexosiran sodium is a siRNA that inhibits ANGPTL3 angiopoietin-related protein 3 synthesis, and can be use for the study of antihyperlipidaemic.
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Solbinsiran
0 ImagesCat. No.: HY-177666CAS No.: 2718150-11-7Synonyms: LY3561774Solbinsiran is a siRNA targeted to hepatic ANGPTL3.
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Cartilostatin 1
0 ImagesCat. No.: HY-P4000CAS No.: 929555-05-5Cartilostatin 1 is an anti-angiogenic peptide. Cartilostatin 1 can be used for the research of anti-angiogenic.
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Vupanorsen sodium scrambled negative control
0 ImagesCat. No.: HY-153497CVupanorsen sodium scrambled negative control is the sequence scrambled negative control of Vupanorsen sodium.
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Anti-ANGPTL8 Antibody
0 ImagesCat. No.: HY-P990336Anti-ANGPTL8 Antibody is a CHO expressed human antibody targeting ANGPTL8. Anti-ANGPTL8 Antibody has a huIgG1-type heavy chain and a huκ-type light chain with a predicted molecular weight (MW) of 150 kDa. An isotype control for Anti-ANGPTL8 Antibody can be found in Human IgG2 kappa, Isotype Control (HY-P99002).
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