Zodasiran sodium
Zodasiran sodium (ARO-ANG3 sodium) is an siRNA targeting ANGPTL3 that mediates RNAi degradation of ANGPTL3 mRNA, reducing hepatic ANGPTL3 protein synthesis and mRNA expression. Zodasiran sodium can be used in research related to diseases such as atherosclerotic cardiovascular disease and mixed dyslipidemia.
For research use only. We do not sell to patients.
- CAS No.: 2232918-74-8
- Formula: C491H603F13N162Na43O309P43S7
- Molecular Weight:16509.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
ANGPTL3 |
In Vitro
In Vivo
Zodasiran (ARO-ANG3) sodium reduces serum TG and total cholesterol after a single subcutaneous administration in hApoC3 transgenic mice[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2232918-74-8
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Molecular Weight 16509.90
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Formula C491H603F13N162Na43O309P43S7
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SMILES
[Zodasiran (sodium)]
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Synonyms
ARO-ANG3 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)