2. Metabolic Enzyme/Protease
  3. ANGPTL
  4. Zodasiran

Zodasiran is a siRNA targeted to ANGPTL3 in the liver.

For research use only. We do not sell to patients.

RNA, ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Gm-Cm-Um-Cm-Am-Am-Cm-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Um-Um-Gm-Am-Um-Cm-Am-Gm-Um-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA), 3'-[O-[cis-4-[(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Cm-sp-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)G-sp-Cm) (1:1)

Zodasiran Chemical Structure

CAS No. : 2232918-66-8

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Based on 1 publication(s) in Google Scholar

Zodasiran Related Antibodies

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ANGPTL3 ANGPTL4 ANGPTL8

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Description

Zodasiran is a siRNA targeted to ANGPTL3 in the liver.

Clinical Trial
Molecular Weight

15564.70

Formula

C491H646F13N162O309P43S7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Zodasiran]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Zodasiran Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zodasiran2232918-66-8ARO-ANG3ANGPTLAngiopoietin-like proteinInhibitorinhibitorinhibit

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