2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. ANGPTL
  5. ANGPTL Activator

ANGPTL Activator

ANGPTL Isoform Comparison

ANGPTL Activator (1):

Cat. No. Product Name Effect Purity
  • HY-103325
    JTE-907
    		Activator 98.54%
    JTE-907 is a selective and orally active cannabinoid CB2 receptor inverse agonist and exerts anti-inflammatory effects. JTE-907 upregulates IL-6, MCP-1, IL-1β, VEGF, ANGPTL4, and TRPV1 in mature adipocytes. JTE-907 downregulates CB1, MCP-1, and IL-1β in preadipocytes. JTE-907 inhibits ear swelling in mice. JTE-907 reverses the protective effects of CB2 agonists and Anandamide (HY-10863) against cytokine-evoked colonic mucosal damage. JTE-907 can be used for the research of allergic dermatitis, obesity, and colitis.