2. Metabolic Enzyme/Protease
  3. ANGPTL
  4. Lexosiran sodium

Lexosiran sodium is a siRNA that inhibits ANGPTL3 angiopoietin-related protein 3 synthesis, and can be use for the study of antihyperlipidaemic.

For research use only. We do not sell to patients.

RNA, ([1′-de(6-amino-9H-purin-9-yl)]A-(5′→5′)-sp-Gm-Am-Am-Um-Gm-Gm-Am-Am-(2′-deoxy-2′-fluoro)G-Gm-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)A-Um-Am-Cm-Um-Cm-Um-Am-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-9-yl)]A), 3′-[O-[1-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-6,10-bis[2-[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]-2-oxoethyl]-1,5,12-trioxo-16-oxa-6,10,13-triazaoctadec-1-yl]-4-piperidinyl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)U-sp-Am-Gm-Am-Gm-(2′-deoxy-2′-fluoro)U-Am-Um-Am-Am-(2′-deoxy-2′-fluoro)C-Cm-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)C-Cm-Am-Um-sp-Um-sp-Cm) (1:1) (sodium)

Lexosiran sodium Chemical Structure

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Other Forms of Lexosiran sodium:

Lexosiran sodium Related Antibodies

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Description

Lexosiran sodium is a siRNA that inhibits ANGPTL3 angiopoietin-related protein 3 synthesis, and can be use for the study of antihyperlipidaemic.

IC50 & Target

ANGPTL3

 

Molecular Weight

15667.9 (free acid)

SMILES

[Lexosiran (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lexosiran sodium Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LexosiranANGPTLAngiopoietin-like proteinInhibitorinhibitorinhibit

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Lexosiran sodium
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HY-185318A
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