2. Protein Tyrosine Kinase/RTK
  3. Insulin Receptor
  4. Z971169476

Z971169476 is a sulfonamide-based protein-RNA interaction inhibitor targeting the KH34 region of insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2/IMP2).

For research use only. We do not sell to patients.

Z971169476

Z971169476 Chemical Structure

CAS No. : 1356662-88-8

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Z971169476 Related Antibodies

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Description

Z971169476 is a sulfonamide-based protein-RNA interaction inhibitor targeting the KH34 region of insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2/IMP2)[1].

In Vitro

Z971169476 (compound 18) exhibits high kinetic solubility (>200 μM in 1% DMSO/PBS), moderate lipophilicity (LogD7.4 1.68), metabolic instability in mouse and human liver microsomes, high stability in mouse and human plasma, >99% plasma protein binding in mouse and human plasma, and very low Caco-2 cell permeability (Papp 0.40 × 10-6 cm/s)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Z971169476 Related Antibodies
Molecular Weight

448.32

Formula

C18H19Cl2NO6S
CAS No.
SMILES

ClC1=C(OCC(C)C)C=CC(NS(=O)(C2=CC(Cl)=C(OCC(O)=O)C=C2)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Z971169476 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z9711694761356662-88-8Z 971169476Z-971169476Insulin ReceptorIGF2BP2/IMP2mouse plasmaKH34 regionIMP2 KH34 domainhuman plasmamouse liver microsomesCaco-2 cellinsulin-like growth factor 2 mRNA binding protein 2human liver microsomesprotein-RNA interaction inhibitorInhibitorinhibitorinhibit

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Z971169476
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HY-181666
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