CETP Antibody (YA9679)
(Synonyms: BPIFF, CETP, CETP_HUMAN, Cholesteryl ester transfer protein, Cholesteryl ester transfer protein plasma, HDLCQ10, Lipid transfer protein I)CETP Antibody (YA9679) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CETP.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000 | 1:1000 |
Product Details
CETP Antibody (YA9679) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CETP.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 55 kDa;
Synthetic peptide of human CETP (aa 251-300).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CETP is involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination[1][2][3][4].
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Expressed by the liver and secreted in plasma. -
Isoforms & Post-Translational Modification
CETP has 2 isoforms, P11597-1: amino acid length is 493, molecular weight is 54756 Da (predicted); P11597-2: amino acid length is 433, molecular weight is 47787 Da (predicted).
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SwissProt ID
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Synonyms
BPIFF, CETP, CETP_HUMAN, Cholesteryl ester transfer protein, Cholesteryl ester transfer protein plasma, HDLCQ10, Lipid transfer protein I
Documentation
References
[1]. Morton RE, et al. Cholesteryl ester transfer proteins from different species do not have equivalent activities. J Lipid Res. 2014 Feb;55(2):258-65. [Content Brief]
[2]. Hesler CB, et al. Monoclonal antibodies to the Mr 74,000 cholesteryl ester transfer protein neutralize all of the cholesteryl ester and triglyceride transfer activities in human plasma. J Biol Chem. 1988 Apr 15;263(11):5020-3. [Content Brief]
[3]. Drayna D, et al. Cloning and sequencing of human cholesteryl ester transfer protein cDNA. Nature. 1987 Jun 18-24;327(6123):632-4. [Content Brief]
[4]. Qiu X, et al. Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules. Nat Struct Mol Biol. 2007 Feb;14(2):106-13. [Content Brief]
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