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GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15917
    DL-Dithiothreitol
    40+ Cited Publications

    DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol

    Biochemical Assay Reagents Disulfidptosis Cancer
    DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond .
    DL-Dithiothreitol
  • HY-B0400
    D-Sorbitol
    2 Publications Verification

    Sorbitol; D-Glucitol

    Environmental Pollutants Endogenous Metabolite Bacterial Others
    D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol
  • HY-150298
    Soquelitinib
    3 Publications Verification

    CPI-818

    Itk Inflammation/Immunology Cancer
    Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8 + cells that possess enhanced T effector function .
    Soquelitinib
  • HY-P0294

    6X His Tag

    Biochemical Assay Reagents Others
    Hexa-His (6X His Tag) is a commonly used affinity tag made up of six histidine residues. HEXA-HIS can bind to affinity chromatography media containing transition metal ions like nickel (Ni 2+) or cobalt (Co 2+), making it useful for protein purification .
    Hexa-His
  • HY-P991503

    AZD0516 antibody

    ADC Antibody Cancer
    Anti-STEAP2 Antibody (AZD0516 antibody) is an antibody targeting six-transmembrane epithelial antigen of the prostate 2 (STEAP2). Anti-STEAP2 Antibody can be used for the synthesis of the ADC molecule AZD0516 (HY-173639). Anti-STEAP2 Antibody can be used in the research of prostate cancer .
    Anti-STEAP2 Antibody
  • HY-17466

    Bonomycin; 6-Demethyl-6-deoxytetracycline

    Bacterial Antibiotic Metabolic Disease Inflammation/Immunology
    Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin .
    Sancycline
  • HY-173639

    Antibody-Drug Conjugates (ADCs) Topoisomerase Apoptosis Cancer
    AZD0516 is a first-in-class antibody-drug conjugate (ADC) targeting six-transmembrane epithelial antigen of the prostate-2 (STEAP2). The anti-STEAP2 monoclonal antibody (mAb) is conjugated via interchain cysteines to a maleimide-reactive, β-glucuronidase-cleavable linker (HY-173635) bearing the topoisomerase 1 inhibitor, Exatecan (HY-13631). AZD0516 can be used for the study of prostate cancer .
    AZD0516
  • HY-138657
    NCGC00378430
    2 Publications Verification

    Phosphatase Cancer
    NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-β signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model .
    NCGC00378430
  • HY-N6831
    Xylohexaose
    1 Publications Verification

    Biochemical Assay Reagents Others
    Xylohexaose is a xylooligosaccharide composed of six xylose residues. Xylohexaose can be produced by hydrolysis of beechwood xylan by AfXynA. Xylohexaose serves as a substrate for the determination of xylan hydrolysis activity .
    Xylohexaose
  • HY-W034566

    Hexaaza-18-crown-6; 1,4,7,10,13,16-Hexaazacyclooctadecane

    Biochemical Assay Reagents Others
    Hexacyclen is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications .
    Hexacyclen
  • HY-N0829
    Shionone
    1 Publications Verification

    Others Inflammation/Immunology
    Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .
    Shionone
  • HY-B0400B

    Sorbito, for cell culture; D-Glucitol, for cell culture

    Environmental Pollutants Biochemical Assay Reagents Others
    D-Sorbitol (D-Glucitol), for cell culture is a six-carbon sugar alcohol that can be used as a sugar substitute. D-Sorbitol, for cell culture serves as an osmotic regulator, cryoprotectant and carbon source in various plant and microbial cell culture media .
    D-Sorbitol, for cell culture
  • HY-W021265

    Cyclohexane-1,2,3,4,5,6-hexol

    Biochemical Assay Reagents Others
    Cyclohexane-1,2,3,4,5,6-hexaol, also known as inositol or inositol, is a cyclic sugar alcohol consisting of a six-carbon ring with six hydroxyl groups. This compound is important for its biological activity and is widely distributed in nature, especially in plant and animal tissues. It plays a role in various physiological processes such as signal transduction, osmoregulation and lipid metabolism. In addition, Cyclohexane-1,2,3,4,5,6-hexaol has potential investigational effects, including improving conditions related to insulin resistance, polycystic ovary syndrome, and mental health conditions. It can also be used as a supplement in animal feed and human nutritional products.
    Cyclohexane-1,2,3,4,5,6-hexaol
  • HY-B0400S1

    Sorbitol-13C; D-Glucitol-13C

    Endogenous Metabolite Others
    D-Sorbitol- 13C is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary s
    D-Sorbitol-13C
  • HY-W021425
    D-Mannosamine hydrochloride
    1 Publications Verification

    (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

    Drug Derivative Metabolic Disease
    D-Mannosamine ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors .
    D-Mannosamine hydrochloride
  • HY-W017690

    Biochemical Assay Reagents Others
    (2E,4E)-Hexa-2,4-dien-1-ol consists of a six-carbon chain with two conjugated double bonds between carbon atoms 2 and 3 and between carbon atoms 4 and 5, and a The hydroxyl group attached to carbon atom 1. This compound has a floral fragrance and can be found in a variety of plants in nature.
    (2E,4E)-Hexa-2,4-dien-1-ol
  • HY-W047710

    Biochemical Assay Reagents Others
    D-Galactal is a monosaccharide that belongs to the class of carbohydrates. It is an aldohexose, which means it has six carbon atoms and an aldehyde functional group. D-Galactal occurs naturally in certain foods such as dairy products, meats and fruits. It can also be synthesized by chemical or enzymatic processes. D-Galactal has various applications in the food industry, especially as a flavoring and sweetening agent. Additionally, it has potential research roles in metabolic disorders, cancer, and inflammation.
    D-Galactal
  • HY-N0918

    Demethoxyyangonin; 5,6-Dehydrokavain

    Monoamine Oxidase JAK IKK STAT NO Synthase Cytochrome P450 Neurological Disease Inflammation/Immunology
    Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant. Desmethoxyyangonin is a selective inhibitor of monoamine oxidase-B (MAO-B) (IC50: 0.123  µM). Desmethoxyyangonin exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways. Desmethoxyyangonin induces CYP3A23 expression and leads to skeletal muscle relaxation .
    Desmethoxyyangonin
  • HY-110135A
    NBI-31772 hydrate
    3 Publications Verification

    IGF-1R Neurological Disease
    NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (Kis=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .
    NBI-31772 hydrate
  • HY-15917S2

    DTT-d6

    Isotope-Labeled Compounds Disulfidptosis Cancer
    DL-Dithiothreitol-d6 is the deuterated form of DL-Dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond .
    DL-Dithiothreitol-d6
  • HY-B0400S16

    Sorbitol-13C6; D-Glucitol-13C6

    Bacterial Endogenous Metabolite Others
    D-Sorbitol- 13C6 is the 13C labeled D-Sorbitol . D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol-13C6
  • HY-118874A

    Apoptosis Bcl-2 Family Cancer
    Oblimersen sodium is a BCL-2 inhibitor targeting BCL-2 RNA. Oblimersen sodium specifically binds to the first six codons of the bcl-2 mRNA sequence, resulting in degradation of bcl-2 mRNA and induces apoptosis by down-regulating expression of Bcl-2. Oblimersen sodium can be used for cancer research .
    Oblimersen sodium
  • HY-P3726

    Integrin Inflammation/Immunology Cancer
    Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) .
    Lys-Gln-Ala-Gly-Asp-Val
  • HY-B0400S

    Sorbitol-d8; D-Glucitol-d8

    Endogenous Metabolite Others
    D-Sorbitol-d8 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol-d8
  • HY-149933

    Cannabinoid Receptor Neurological Disease
    AM841 is a high-affinity electrophilic ligand. AM841 interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor. AM841 reduces Forskolin (HY-15371)-stimulated cAMP accumulation. AM841 also slows gastrointestinal motility .
    AM841
  • HY-B0400R

    Sorbitol (Standard); D-Glucitol (Standard)

    Reference Standards Endogenous Metabolite Bacterial Others
    D-Sorbitol (Standard) is the analytical standard of D-Sorbitol. This product is intended for research and analytical applications. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol (Standard)
  • HY-W017567

    trans-2-Hexenoic Acid Ethyl Ester

    Biochemical Assay Reagents Others
    Ethyl (E)-2-hexenoate consists of a six-carbon chain with a double bond between the 2nd and 3rd carbon atoms, an ethyl ester group attached to the 1st carbon atom, and a A methyl group connected by 4 carbon atoms. This compound has a fruity, sweet or floral aroma and is commonly used as a flavoring in foods such as baked goods, confectionary and beverages.
    Ethyl (E)-2-hexenoate
  • HY-174959D

    Biochemical Assay Reagents Others
    6-Arm-PEG3400-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
    6-Arm-PEG3400-NHS
  • HY-P4247

    Amino Acid Derivatives Others
    Hexa-arginine, consisting of six arginines, is a polycationic peptide that can penetrate cells efficiently and is mainly used for the intracellular delivery of low-molecular-weight agents, biomolecules, and particles .
    Hexaarginine
  • HY-76203

    Drug Intermediate Others
    2-Coumaranone is a bicyclic heteroaromatic compound in which a six-membered benzene ring is annulated with a five-membered γ-butyrolactone ring. 2-Coumaranone can be used to synthesize chemiluminescent and fluorescent dyes .
    2-Coumaranone
  • HY-114856

    Biochemical Assay Reagents Others
    DTBT is a six-membered heterocyclic ring that is commonly used in the preparation of organic electronic devices, such as P-type organic semiconductors (OFETs) and P-type organic photodiodes (OLEDs). DTBT has good performance in electron transmission and photoelectric conversion. DTBT polymerizes to form donor-acceptor polymers, which are used to prepare solar cells .
    DTBT
  • HY-118874

    Bcl-2 Family Apoptosis Cancer
    Oblimersen is a BCL-2 inhibitor targeting BCL-2 RNA. Oblimersen specifically binds to the first six codons of the bcl-2 mRNA sequence, resulting in degradation of bcl-2 mRNA and induces apoptosis by down-regulating expression of Bcl-2. Oblimersen can be used for cancer research .
    Oblimersen
  • HY-P11012

    SARS-CoV Infection
    EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species. EK1 shows substantially improved pan-CoV fusion inhibitory activity. EK1 potently inhibits SARS-CoV-2. EK1 can form a stable six-helix bundle (6HB) structure with both short α-hCoV and long β-hCoV N-terminal heptad repeats .
    EK1
  • HY-P0148

    Hexaglycine

    Bacterial Others
    Gly6 (Hexaglycine) is a linear glycine oligopeptide with six glycines .
    Gly6
  • HY-N7701D

    Others Infection
    L-Hexaguluronic acid is a linear polysaccharide copolymer composed of six L-guluronic acid (G) .
    L-Hexaguluronic acid
  • HY-174959B

    Biochemical Assay Reagents Others
    6-Arm-PEG1000-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
    6-Arm-PEG1000-NHS
  • HY-174959

    Biochemical Assay Reagents Others
    6-Arm-PEG400-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
    6-Arm-PEG400-NHS
  • HY-174959E

    Biochemical Assay Reagents Others
    6-Arm-PEG5000-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
    6-Arm-PEG5000-NHS
  • HY-174959A

    Biochemical Assay Reagents Others
    6-Arm-PEG600-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
    6-Arm-PEG600-NHS
  • HY-15917S

    DTT-d10

    Isotope-Labeled Compounds Disulfidptosis Cancer
    DL-Dithiothreitol-d10 is the deuterated form of DL-Dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond .
    DL-Dithiothreitol-d10
  • HY-112653A

    8-Hydroxy-5(Z),9(E),11(Z),14(Z)-eicosatetraenoic acid

    Endogenous Metabolite Metabolic Disease
    (±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of Arachidonic acid (HY-109590). The biological activity of (±)8-HETE is likely to resemble that of its constituent enantiomers (8(R)-HETE and 8(S)-HETE).
    (±)8-HETE
  • HY-175038

    Fungal Infection
    Oomycete-IN-1 (Compound X4) is a selective inhibitor targeting the PH domain of PcORP1 in Phytophthora species. Oomycete-IN-1 shows EC50 values ranging from 1 to 4 μg/mL against six oomycetes. Oomycete-IN-1 disrupts lipid transport and metabolism, leading to mycelium hyperplasia and cell membrane ruffling in P. capsici. Oomycete-IN-1 can be used in the research of preventing and controlling oomycete diseases (such as P. capsici infection) .
    Oomycete-IN-1
  • HY-17466A

    Bonomycin hydrochloride; 6-Demethyl-6-deoxytetracycline hydrochloride

    Antibiotic Bacterial Metabolic Disease Inflammation/Immunology
    Sancycline (6-Demethyl-6-deoxytetracycline) hydrochloride acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline hydrochloride, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin .
    Sancycline hydrochloride
  • HY-RS12959

    Small Interfering RNA (siRNA) Others

    SIX2 Human Pre-designed siRNA Set A contains three designed siRNAs for SIX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SIX2 Human Pre-designed siRNA Set A
    SIX2 Human Pre-designed siRNA Set A
  • HY-RS21434

    Small Interfering RNA (siRNA) Others

    Six4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Six4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Six4 Mouse Pre-designed siRNA Set A
    Six4 Mouse Pre-designed siRNA Set A
  • HY-RS12958

    Small Interfering RNA (siRNA) Others

    SIX1 Human Pre-designed siRNA Set A contains three designed siRNAs for SIX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SIX1 Human Pre-designed siRNA Set A
    SIX1 Human Pre-designed siRNA Set A
  • HY-RS17696

    Small Interfering RNA (siRNA) Others

    Six1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Six1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Six1 Mouse Pre-designed siRNA Set A
    Six1 Mouse Pre-designed siRNA Set A
  • HY-RS12963

    Small Interfering RNA (siRNA) Others

    SIX6 Human Pre-designed siRNA Set A contains three designed siRNAs for SIX6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SIX6 Human Pre-designed siRNA Set A
    SIX6 Human Pre-designed siRNA Set A
  • HY-RS12962

    Small Interfering RNA (siRNA) Others

    SIX5 Human Pre-designed siRNA Set A contains three designed siRNAs for SIX5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SIX5 Human Pre-designed siRNA Set A
    SIX5 Human Pre-designed siRNA Set A
  • HY-RS26457

    Small Interfering RNA (siRNA) Others

    Six2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Six2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Six2 Rat Pre-designed siRNA Set A
    Six2 Rat Pre-designed siRNA Set A

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