2. Natural Products
  3. Plants Disease Research Fields Terpenoids
  4. Leguminosae Inflammation/Immunology Compositae Diterpenoids
  5. Sesbania vesicaria (Jacq.) Elliott
  6. Shionone

Shionone 

Cat. No.: HY-N0829 Purity: ≥98.0%
COA Handling Instructions

Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure.

For research use only. We do not sell to patients.

Shionone Chemical Structure

Shionone Chemical Structure

CAS No. : 10376-48-4

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1 mg USD 42 In-stock
5 mg USD 90 In-stock
10 mg USD 150 In-stock
20 mg USD 250 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Shionone Related Antibodies

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Description

Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities[1][2]. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure[1].

In Vivo

Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR male mice[1]
Dosage: 80 mg/kg
Administration: Orally administration; 3 days; once daily
Result: Reduced the ear edema for 11.3% by use shionone.
Molecular Weight

426.72

Appearance

Solid

Formula

C30H50O
CAS No.
SMILES

O=C1[C@H](C)[C@@]2(C)CC[C@]3([H])[C@@]4(C)CC[C@](CC/C=C(C)/C)(C)C[C@]4(C)CC[C@@]3(C)[C@]2([H])CC1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

Ethanol : 2 mg/mL (4.69 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3435 mL 11.7173 mL 23.4346 mL
5 mM --- --- ---
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% Saline

    Solubility: 0.77 mg/mL (1.80 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in Saline)

    Solubility: 0.77 mg/mL (1.80 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% EtOH    90% Corn Oil

    Solubility: ≥ 0.77 mg/mL (1.80 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (246 KB) HNMR (202 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Shionone10376-48-4OthersCough Anti-inflammatoryInhibitorinhibitorinhibit

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