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  4. (Z)-γ-Bisabolene

(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus.

For research use only. We do not sell to patients.

(Z)-γ-Bisabolene

(Z)-γ-Bisabolene Chemical Structure

CAS No. : 13062-00-5

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(Z)-γ-Bisabolene Related Antibodies

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Description

(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus[1].

In Vivo

(Z)-γ-bisabolene (1-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Anopheles stephensi with an LC50 of 2.04 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.79[1].
(Z)-γ-bisabolene (1-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Aedes aegypti with an LC50 of 2.26 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.83[1].
(Z)-γ-bisabolene (1-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Culex quinquefasciatus with an LC50 of 2.47 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.85[1].
(Z)-γ-bisabolene (2-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Anopheles subpictus with an LC50 of 4.09 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.78[1].
(Z)-γ-bisabolene (2-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Aedes albopictus with an LC50 of 4.50 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.82[1].
(Z)-γ-bisabolene (2-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Culex tritaeniorhynchus with an LC50 of 4.87 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.83[1].
(Z)-γ-bisabolene (1-10 μg/mL; 24 h) potently kills 3rd instar larvae of Anopheles stephensi (LC50 = 2.04 μg/mL), Aedes aegypti (LC50 = 2.26 μg/mL), Culex quinquefasciatus (LC50 = 2.47 μg/mL), Anopheles subpictus (LC50 = 4.09 μg/mL), Aedes albopictus (LC50 = 4.50 μg/mL), and Culex tritaeniorhynchus (LC50 = 4.87 μg/mL)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 3rd instar larvae; 5-7 day old gravid adult females[1]
Dosage: 1, 2, 3, 4, 5 μg/mL (larvicidal); 5, 10, 15, 20, 25 μg/mL (oviposition deterrence)
Administration: aquatic exposure (larvicidal, 24 h); aquatic exposure (oviposition deterrence, 72 h)
Result: Achieved LC50 2.04-4.87 μg/mL and LC90 4.06-9.16 μg/mL against six mosquito larvae.
Caused 20.7%-100.0% mortality at 1-10 μg/mL against all tested mosquito larvae.
Showed ER 72.07%-92.03% and OAI -0.56 to -0.85 for oviposition deterrence against six vectors.
Molecular Weight

204.36

Formula

C15H24
CAS No.
SMILES

C(\CCC=C(C)C)(/C)=C\1/CCC(C)=CC1
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(Z)-γ-Bisabolene Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Z)-γ-Bisabolene13062-00-5Insecticidejapanese encephalitisAnopheles subpictusdengueAedes albopictusCulex tritaeniorhynchusCulex quinquefasciatusAnopheles stephensiAedes aegyptimalariaGalinsoga parvifloraInhibitorinhibitorinhibit

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