(Z)-γ-Bisabolene
(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus.
For research use only. We do not sell to patients.
- CAS No.: 13062-00-5
- Formula: C15H24
- Molecular Weight:204.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
(Z)-γ-bisabolene (1-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Aedes aegypti with an LC50 of 2.26 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.83[1].
(Z)-γ-bisabolene (1-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Culex quinquefasciatus with an LC50 of 2.47 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.85[1].
(Z)-γ-bisabolene (2-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Anopheles subpictus with an LC50 of 4.09 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.78[1].
(Z)-γ-bisabolene (2-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Aedes albopictus with an LC50 of 4.50 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.82[1].
(Z)-γ-bisabolene (2-25 μg/mL; aquatic exposure; 24-72 h) exhibits high larvicidal activity against Culex tritaeniorhynchus with an LC50 of 4.87 μg/mL and strong oviposition deterrent activity at 25 μg/mL with an OAI of -0.83[1].
(Z)-γ-bisabolene (1-10 μg/mL; 24 h) potently kills 3rd instar larvae of Anopheles stephensi (LC50 = 2.04 μg/mL), Aedes aegypti (LC50 = 2.26 μg/mL), Culex quinquefasciatus (LC50 = 2.47 μg/mL), Anopheles subpictus (LC50 = 4.09 μg/mL), Aedes albopictus (LC50 = 4.50 μg/mL), and Culex tritaeniorhynchus (LC50 = 4.87 μg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:3rd instar larvae; 5-7 day old gravid adult females[1]
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Dosage:1, 2, 3, 4, 5 μg/mL (larvicidal); 5, 10, 15, 20, 25 μg/mL (oviposition deterrence)
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Administration:aquatic exposure (larvicidal, 24 h); aquatic exposure (oviposition deterrence, 72 h)
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Result:Achieved LC50 2.04-4.87 μg/mL and LC90 4.06-9.16 μg/mL against six mosquito larvae.
Caused 20.7%-100.0% mortality at 1-10 μg/mL against all tested mosquito larvae.
Showed ER 72.07%-92.03% and OAI -0.56 to -0.85 for oviposition deterrence against six vectors.
Chemical Information
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CAS No. 13062-00-5
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Molecular Weight 204.36
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Formula C15H24
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SMILES
C(\CCC=C(C)C)(/C)=C\1/CCC(C)=CC1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Z)-γ-Bisabolene Related Classifications
HY-N11234A Related Classifications
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