(S)-Norcoclaurine synthase

The reaction makes a six-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates. (S)-Norcoclaurine synthase (EC 3.5.99.14) , formerly known as (S)-norlaudanosoline synthase, will also catalyse the reaction of 4-(2-aminoethyl) benzene-1,2-diol + (3,4-dihydroxyphenyl) acetaldehyde to form (S)-norlaudanosoline.

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