1. Cytoskeleton
  2. Integrin
  3. Lys-Gln-Ala-Gly-Asp-Val

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs).

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Custom Peptide Synthesis

Lys-Gln-Ala-Gly-Asp-Val

Lys-Gln-Ala-Gly-Asp-Val 화학구조

CAS No. : 80755-87-9

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 견적 받기
100 mg   견적 받기  
200 mg   견적 받기  

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제품 설명

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].

In Vitro

Lys-Gln-Ala-Gly-Asp-Val (2 nM) improves smooth muscle cell adhesion and growth on polymers[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

616.66

화학식

C25H44N8O10

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Gln-Ala-Gly-Asp-Val

Sequence Shortening

KQAGDV

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

H2O : ≥ 100 mg/mL (162.16 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6216 mL 8.1082 mL 16.2164 mL
5 mM 0.3243 mL 1.6216 mL 3.2433 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6216 mL 8.1082 mL 16.2164 mL 40.5410 mL
5 mM 0.3243 mL 1.6216 mL 3.2433 mL 8.1082 mL
10 mM 0.1622 mL 0.8108 mL 1.6216 mL 4.0541 mL
15 mM 0.1081 mL 0.5405 mL 1.0811 mL 2.7027 mL
20 mM 0.0811 mL 0.4054 mL 0.8108 mL 2.0270 mL
25 mM 0.0649 mL 0.3243 mL 0.6487 mL 1.6216 mL
30 mM 0.0541 mL 0.2703 mL 0.5405 mL 1.3514 mL
40 mM 0.0405 mL 0.2027 mL 0.4054 mL 1.0135 mL
50 mM 0.0324 mL 0.1622 mL 0.3243 mL 0.8108 mL
60 mM 0.0270 mL 0.1351 mL 0.2703 mL 0.6757 mL
80 mM 0.0203 mL 0.1014 mL 0.2027 mL 0.5068 mL
100 mM 0.0162 mL 0.0811 mL 0.1622 mL 0.4054 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Lys-Gln-Ala-Gly-Asp-Val
Cat. No.:
HY-P3726
수량:
MCE Japan Authorized Agent: