DL-Dithiothreitol-d10-1
DL-Dithiothreitol-d10-1 is the deuterated form of DL-dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-Dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond.
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- No. CAS: 203633-21-0
- Fòrmula: C4D10O2S2
- Peso molecular:164.31
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 203633-21-0
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Unlabeled CAS 3483-12-3
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Peso molecular 164.31
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Fòrmula C4D10O2S2
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SMILES
[2H]SC([2H])([2H])[C@](O[2H])([2H])[C@@](O[2H])([2H])C([2H])([2H])S[2H]
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Synonyms
DTTl-d10-1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24(1): 183. [Content Brief]
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Topics Disulfidptosis: Actin Cytoskeleton Collapse Under Disulfide Stress
Disulfidptosis is a recently identified form of regulated cell death driven by disulfide stress and characterized by collapse of the actin cytoskeleton rather than by the canonical mechanisms that define apoptosis, necroptosis, ferroptosis, pyroptosis, or other established cell death programs.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DL-Dithiothreitol-d10-1 Related Classifications
HY-15917S1 Related Classifications
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