2. Anti-infection
  3. Bacterial Antibiotic Parasite
  4. Chlortetracycline hydrochloride

Chlortetracycline hydrochloride  (Synonyms: 7-Chlorotetracycline hydrochloride)

Cat. No.: HY-B1327 Pureza: 95.0%
COA
SDS
Instrucciones de manejo Technical Support

Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes.

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Chlortetracycline hydrochloride

Chlortetracycline hydrochloride Estructura química

No. CAS : 64-72-2

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1 g En stock
5 g En stock
10 g   Obtener un presupuesto  
50 g   Obtener un presupuesto  

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This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 7 publication(s) in Google Scholar

Other Forms of Chlortetracycline hydrochloride:

Chlortetracycline hydrochloride Related Antibodies

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Descripciòn

Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes[1][2][3][4].

IC50 & Target

Tetracycline

 

In Vitro

Chlortetracycline hydrochloride (10, 50, 100, 200 mg/L, 18 days) inhibits methane (a main component of biogas) production and is degradated and metabolized by anaerobic digestion (AD) at high concentrations and incubation temperatures[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chlortetracycline hydrochloride Related Antibodies
In Vivo

Chlortetracycline hydrochloride (50 mg/kg, p.o., administration for 42 consecutive days) significantly increases the IgM antibody levels and decreases the IgA antibody levels in serum of mice[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SPF level Kunming mice (KM)[4]
Dosage: 50 mg/kg
Administration: p.o., administration for 42 consecutive days
Result: Significantly increased the IgM antibody levels, decreased the IgA antibody levels and not influenced IgG antibody levels in serum of mice.
Peso molecular

515.34

Fòrmula

C22H24Cl2N2O8
No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N.[H]Cl
Structure Classification
Initial Source

Streptomyces aureofaciens
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

DMSO : 5 mg/mL (9.70 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 5 mg/mL (9.70 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9405 mL 9.7023 mL 19.4047 mL
5 mM 0.3881 mL 1.9405 mL 3.8809 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 95.0%

SDS (396 KB)

COA (257 KB) HNMR (309 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.9405 mL 9.7023 mL 19.4047 mL 48.5117 mL
5 mM 0.3881 mL 1.9405 mL 3.8809 mL 9.7023 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Chlortetracycline hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chlortetracycline64-72-27-ChlorotetracyclineBacterialAntibioticParasiteorally activemethanogenic bacteria inhibitorbactericidal effectsantibioticribosomesInhibitorinhibitorinhibit

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Nombre del producto:
Chlortetracycline hydrochloride
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HY-B1327
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