2. Others Neuronal Signaling GPCR/G Protein Metabolic Enzyme/Protease Apoptosis
  3. Ferroptosis Environmental Pollutants mGluR Endogenous Metabolite
  4. L-Glutamine

L-グルタミン  (Synonyms: L-Glutamine; L-Glutamic acid 5-amide)

製品番号: HY-N0390 純度: 98.0%
COA 取扱説明書 Technical Support

L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 56-85-9

容量 価格（税別） 在庫状況 数量
25 g $30 在庫あり
50 g $48 在庫あり
100 g $77 在庫あり
500 g $200 在庫あり
1000 g $320 在庫あり
> 100 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 27 publication(s) in Google Scholar

Other Forms of L-Glutamine:

L-グルタミン 関連抗体

Top Publications Citing Use of Products

    L-Glutamine purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 6;16(1):72.  [Abstract]

    The mRNA level of Arg1 in BMDM infected with lentivirus carrying shRNA-NC or shRNA-Blimp-1, and treated with Glutamine (20 mM; 48 h).

    L-Glutamine purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 6;16(1):72.  [Abstract]

    The survival rates of CLP mice intraperitoneally injected with macrophage-targeted AAV carrying shRNA-NC or shRNA-Blimp-1, and treated with Glutamine (0.75 g/kg; ip).

    L-Glutamine purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 6;16(1):72.  [Abstract]

    Glutamine (0.75 g/kg; ip). Percentage of M2 macrophages in PLF cells.

    L-Glutamine purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 May:71:103112.  [Abstract]

    Cells were infected with PDCoV in media containing different concentrations of Glutamine (0, 1, 2, or 4 mM; 18 h).

    L-Glutamine purchased from MedChemExpress. Usage Cited in: Cell Rep. 2019 Jul 9;28(2):512-525.e6.   [Abstract]

    MTT assay of PC9 cells treated with or without ethylestered GSH (100 μM), or L-Glutamine (10 mM) , together with the indicated doses of GEF for 72 h.

    mGluR アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

    Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Human Endogenous Metabolite Microbial Metabolite

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

    IC50 & Target[4]

    mGluR

     

    Human Endogenous Metabolite

     

    体外実験

    L-Glutamine is important as a precursor for peptide and protein synthesis, amino sugar synthesis, purine and pyrimidine and thus nucleic acid and nucleotide synthesis, and also provides a source of carbons for oxidation in some cells. L-Glutamine is the most abundant extracellular amino acid in vivo (0.7 mM compared to an approximate L-glutamate concentration of 20 μM)[1].
    In BRIN-BD11 cells, culture for 24 h with 10 mM L-Glutamine compared with 1 mM resulted in substantial changes in gene expression with 148 genes upregulated more than 1.8-fold, and 18 downregulated more than 1.8-fold, including many genes involved in cellular signaling, metabolism, gene regulation, and the insulin-secretory response. L-Glutamine increases the activity of the Ca2+ regulated phosphatase calcineurin and the transcription factor Pdx1[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    L-グルタミン 関連抗体
    臨床実験
    分子量

    146.15

    分子式

    C5H10N2O3
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    N[C@@H](CCC(N)=O)C(O)=O
    Structure Classification
    Initial Source
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    溶剤 & 溶解度
    体外: 

    H2O : 33.33 mg/mL (228.05 mM; ultrasonic and adjust pH to 1 with HCl)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 6.8423 mL 34.2114 mL 68.4229 mL
    5 mM 1.3685 mL 6.8423 mL 13.6846 mL
    10 mM 0.6842 mL 3.4211 mL 6.8423 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    体内:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 7.69 mg/mL (52.62 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    純度とドキュメンテーション

    純度: 99.2%

    COA (244 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 6.8423 mL 34.2114 mL 68.4229 mL 171.0571 mL
    5 mM 1.3685 mL 6.8423 mL 13.6846 mL 34.2114 mL
    10 mM 0.6842 mL 3.4211 mL 6.8423 mL 17.1057 mL
    15 mM 0.4562 mL 2.2808 mL 4.5615 mL 11.4038 mL
    20 mM 0.3421 mL 1.7106 mL 3.4211 mL 8.5529 mL
    25 mM 0.2737 mL 1.3685 mL 2.7369 mL 6.8423 mL
    30 mM 0.2281 mL 1.1404 mL 2.2808 mL 5.7019 mL
    40 mM 0.1711 mL 0.8553 mL 1.7106 mL 4.2764 mL
    50 mM 0.1368 mL 0.6842 mL 1.3685 mL 3.4211 mL
    60 mM 0.1140 mL 0.5702 mL 1.1404 mL 2.8510 mL
    80 mM 0.0855 mL 0.4276 mL 0.8553 mL 2.1382 mL
    100 mM 0.0684 mL 0.3421 mL 0.6842 mL 1.7106 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    L-Glutamine Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-Glutamine56-85-9L-Glutamic acid 5-amideFerroptosisEnvironmental PollutantsmGluREndogenous MetaboliteEnvironmental ContaminantsMetabotropic glutamate receptorsInhibitorinhibitorinhibit

    最近チェックした製品:

    オンラインお問い合わせ

    Your information is safe with us. * Required Fields.

    製品名

    		  

    カスタマ需要量 *

    お名前 *

    		 

    タイトル

    メールアドレス *

    		 

    電話番号 *

    デパートメント

    		 

    組纖名 *

    市区町村

    都道府県

    国或いは地域 *

    		      

    必ず会社名を記載ください。個人への返信は行いません。

    備考

    バルクお問い合わせ

    Inquiry Information

    製品名:
    L-Glutamine
    製品番号:
    HY-N0390
    数量:
    MCE 日本正規代理店:

    カスタマーレビュー

    Thank You for Your Feedback!

    Request for HNMR Report

    Please fill out this form to request the QC report. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

    製品名

    		  

    Lot #

    お名前 *

    		 

    メールアドレス *

    電話番号 *

    		 

    部門 *

    組纖名 *

    		 

    国或いは地域 *

    備考

    Request for HNMR Report

    We have received your request and will respond to you as soon as possible.