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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
F-actin
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "F-actin" in MCE Product Catalog:
100
100 Publications Verification
Cat. No.: HY-N6682
CAS No.: 22144-77-0
Synonyms: Zygosporin A; NSC 209835
Target:
47
Target:
25
25 Cited Publications
Cat. No.: HY-P0028
CAS No.: 17466-45-4
Target:
Research Areas:
9
9 Cited Publications
Cat. No.: HY-P0027
CAS No.: 102396-24-7
Category:
Antifungal Marine natural products Disease Research Other Antibiotics Infection Monophenols Animals Antibiotics Cyclopeptides Phenols Sponge Anticancer Disease Research Fields
Target:
8
6
1
1 Cited Publications
Cat. No.: HY-156675A
Purity: 99.34%
Target:
Microtubule/Tubulin Eukaryotic Initiation Factor (eIF) HSP Caspase Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
Plecstatin-1 hydrochloride is a metal complex that drives the aggregation and collapse of the plectin network, and disrupts the cytoskeletal structures of α‑tubulin and F‑actin. Plecstatin-1 hydrochloride triggers oxidative stress, mediates the phosphorylation of eIF2α, and induces molecular features associated with immunogenic cell death, including calreticulin membrane exposure, membrane localization of HSP70/HSP90, ATP secretion, and HMGB‑1 release. Plecstatin-1 hydrochloride induces apoptosis via the intrinsic mitochondrial pathway and exerts anti-invasive activity. Plecstatin-1 hydrochloride inhibits sphere proliferation and reduces clonogenicity in the 3D tumor spheroid model of colon cancer cells. Plecstatin-1 hydrochloride is applicable to relevant research on colorectal cancer .
Cat. No.: HY-W002112
CAS No.: 5746-86-1
Synonyms: Nornicotine
Cat. No.: HY-P2031
CAS No.: 26645-35-2
Target:
Cat. No.: HY-105174A
CAS No.: 1628202-19-6
Research Areas:
Cat. No.: HY-B0426A
CAS No.: 140462-76-6
Synonyms: ALO4943A; KW4679
Category:
Alkaloids Other Alkaloids Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-N6744
CAS No.: 50335-03-0
Cat. No.: HY-W062109
CAS No.: 113806-05-6
Category:
Alkaloids Other Alkaloids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-168336
CAS No.: 2909474-29-7
Target:
Research Areas:
E0924G is an orally active activator for PPARδ with EC50 of 2.82 μM. E0924G promotes the upregulation of osteoprotegerin (OPG) with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized (OVX) and age-related osteoporosis models .
Cat. No.: HY-W002112S
CAS No.: 66148-18-3
Synonyms: Nornicotine-d4
Cat. No.: HY-116312
CAS No.: 510774-50-2
Synonyms: 8-CPT-2'-O-Me-cAMP
Target:
Research Areas:
8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP), an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM). 8-pCPT-2′-O-Me-cAMP stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration .
Cat. No.: HY-156675
CAS No.: 2119725-22-1
Target:
Microtubule/Tubulin Eukaryotic Initiation Factor (eIF) HSP Caspase Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
Plecstatin‑1 is a metal complex that drives the aggregation and collapse of the plectin network, and disrupts the cytoskeletal structures of α‑tubulin and F‑actin. Plecstatin-1 triggers oxidative stress, mediates the phosphorylation of eIF2α, and induces molecular features associated with immunogenic cell death, including calreticulin membrane exposure, membrane localization of HSP70/HSP90, ATP secretion, and HMGB‑1 release. Plecstatin-1 induces apoptosis via the intrinsic mitochondrial pathway and exerts anti-invasive activity. Plecstatin‑1 inhibits sphere proliferation and reduces clonogenicity in the 3D tumor spheroid model of colon cancer cells. Plecstatin-1 is applicable to relevant research on colorectal cancer .
Cat. No.: HY-W062109S
CAS No.: 1231979-85-3
Cat. No.: HY-P10993
CAS No.: 1407967-57-0
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
