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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

tobacco cells

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Peptides

14

Natural
Products

3

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0262
    Oxalic acid, 99%
    1 Publications Verification

    Ethanedioic acid

    		 Environmental Pollutants Endogenous Metabolite Infection Inflammation/Immunology
    Oxalic acid, 99% (Ethanedioic acid) is a dicarboxylic acid found in a wide variety of plants. Oxalic acid, 99% shows antioxidant acyivity and suppresses lipid peroxidation. Oxalic acid, 99% is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid, 99% exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease, varroatosis and inflammatory diseases .
    Oxalic acid, 99%
  • HY-100958
    4-DAMP
    4 Publications Verification

    4-DAMP methiodide

    		 mAChR Apoptosis MMP EGFR Interleukin Related Inflammation/Immunology Cancer
    4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .
    4-DAMP
  • HY-P10533
    Cysteine peptide

    		Tyrosinase Others
    Cysteine peptide is a tyrosinase inhibitor with skin-whitening, antioxidant and multi-regulatory activities. Cysteine peptide inhibits enzyme activity and blocks melanin transport, effectively reducing UV-B-induced skin erythema and pigmentation. Cysteine peptide synergistically maintains skin health by quenching ROS, resisting oxidative stress and promoting pheomelanin production. Cysteine peptide safely prevents daily ultraviolet damage and supports moderate sun exposure for vitamin D synthesis. Cysteine peptide also acts as a plant signaling factor to regulate vegetative growth, development and stress resistance responses .
    Cysteine peptide
  • HY-P5712
    Gramicidin S
    1 Publications Verification

    Gramicidin soviet

    		 Antibiotic Bacterial Na+/K+ ATPase Infection
    Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC50s of 41 μM, 24 μM, and 3 μM for Na +/K +-ATPase, tobacco leaf plasma membrane Mg 2+/K +-ATPase, and rat heart plasma membrane Ca 2+-ATPase, respectively .
    Gramicidin S
  • HY-B1972
    Napropamide

    Napropamid

    		 Environmental Pollutants DNA/RNA Synthesis Herbicide Others
    Napropamide (Napropamid) is an amide herbicide that can be used to control weeds in fruits, vegetables, tobacco, and ornamental plants. Napropamide mainly exerts its effect by inhibiting DNA synthesis and cell division. Napropamide has moderate to high persistence in the field, with a half-life of 24-131 days, and is prone to photodegradation .
    Napropamide
  • HY-B1532
    Anabasine

    (S)-Anabasine; (+)-Anabasine

    		 Environmental Pollutants nAChR Neurological Disease
    Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine
  • HY-41404
    Piperonylic acid

    2H-1,3-benzodioxole-5-carboxylic acid

    		 Cytochrome P450 Interleukin Related EGFR IGF-1R Infection Others Cancer
    Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities .
    Piperonylic acid
  • HY-34516
    D-Ornithine hydrochloride

    (R)-Ornithine hydrochloride

    		 Endogenous Metabolite Bacterial Metabolic Disease
    D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .
    D-Ornithine hydrochloride
  • HY-W016393
    Dihydroconiferyl alcohol

    		Endogenous Metabolite Others
    Dihydroconiferyl alcohol is a cell division factor. Dihydroconiferyl alcohol can be isolated from the American sycamore (Acer pseudoplatanus L.). Dihydroconiferyl alcohol inhibits the degradation of Indole-3-acetic acid (HY-18569). Dihydroconiferyl alcohol can stimulate the growth of soybean and tobacco callus tissue and synergistically enhance Indole-3-acetic acid-induced hypocotyl elongation in cucumber. Dihydroconiferyl alcohol can be used in the research of plant growth regulation .
    Dihydroconiferyl alcohol
  • HY-W001084
    Methyl 4-hydroxyphenylacetate

    		Others Infection Cancer
    Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate
  • HY-N1033
    12-Hydroxyjasmonic acid

    		Phytohormone Drug Metabolite Glycosyltransferase Infection
    12-Hydroxyjasmonic acid is a metabolite of Jasmonic acid (HY-122464A) and an inducer of defense responses. 12-Hydroxyjasmonic acid can be isolated from potato leaflets. During the response of sugar beet plants to Cercospora beticola infection, 12-Hydroxyjasmonic acid is released through deglycosylation of its glucoside form and participates in the Jasmonic acid-mediated defense signaling pathway. 12-Hydroxyjasmonic acid mediates changes in source-sink relationships during pathogen infection, prioritizing the activation of defense processes over growth processes. 12-Hydroxyjasmonic acid serves as a substrate for salicylic acid Glycosyltransferases in tobacco and rice. 12-Hydroxyjasmonic acid can induce leaflet closure in Samanea saman. 12-Hydroxyjasmonic acid acts as a potato tuber-inducing substance. 12-Hydroxyjasmonic acid does not induce protoplast shrinkage in extensor motor cells of Samanea saman. 12-Hydroxyjasmonic acid can be used in studies related to brown spot disease .
    12-Hydroxyjasmonic acid
  • HY-N7659
    Glucobrassicin

    		Phytohormone Apoptosis Microtubule/Tubulin Cancer
    Glucobrassicin is an indole-based anticancer agent and plant growth-regulating hormone. Glucobrassicin exerts its biological activity by disrupting the integrity of microtubule networks in both plant and mammalian cells. At high concentrations, Glucobrassicin inhibits seed germination and root growth; it can also specifically induce apoptosis in mammalian cancer cells and interfere with the intercellular transmission of viruses that rely on microtubules. In plants, Glucobrassicin can be catalyzed by myrosinase to release growth-regulating substances, exhibiting a concentration-dependent growth-regulating effect .
    Glucobrassicin
  • HY-W683760
    N-Nitrosonornicotine

    (2S)-N'-Nitrosonornicotine

    		 DNA/RNA Synthesis Cancer
    N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
    N-Nitrosonornicotine
  • HY-117085
    Lobaric acid

    		Phosphatase TMV Lipoxygenase Cancer
    Lobaric acid is a depsipeptide metabolite isolated from Stereocaulon lichen with antioxidant, antiproliferative, antiviral and enzyme inhibitory activities. Lobaric acid scavenges superoxide free radicals (IC50=97.9 μM) and inhibits cancer cell proliferation (EC50 of 15.2-63.9 μg/mL against leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic and lung cancer cell lines). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50=0.87 μM for human recombinant enzyme) and 12(S)-HETE produced by 12(S)-lipoxygenase (IC50=28.5 μM). Lobaric acid (250 μM) also reduced pathological changes in tobacco leaves infected with tobacco mosaic virus (TMV).
    Lobaric acid
  • HY-121255
    (-)-Cryptopleurine

    (R)-Cryptopleurine; NSC 19912

    		 TMV Cancer
    (–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
    (-)-Cryptopleurine
  • HY-Y0262A
    Oxalic acid diammonium monohydrate
    1 Publications Verification

    Ethanedioic acid diammonium monohydrate

    		 Environmental Pollutants Endogenous Metabolite Infection Inflammation/Immunology
    Oxalic acid (Ethanedioic acid) diammonium monohydrate is a dicarboxylic acid found in a wide variety of plants.
    Oxalic acid diammonium monohydrate shows antioxidant acyivity and suppresses lipid peroxidation.
    Oxalic acid diammonium monohydrate is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid diammonium monohydrate exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease varroatosis and inflammatory diseases .
    Oxalic acid diammonium monohydrate
  • HY-119963A
    trans-β-Terpineol

    		Bacterial Infection Inflammation/Immunology
    trans-β-Terpineol is a cyclic monoterpene alcohol present in Greek propolis and the essential oil of Peganum harmala seeds, with biological activities. trans-β-Terpineol serves as a substrate for biotransformation in tobacco suspension cells, where allylic hydroxylation occurs at specific sites. trans-β-Terpineol can be isolated from the leaves of Euryops arabicus. Terpineol (HY-N7851) exhibits antioxidant and antibacterial activities, and trans-β-terpineol is the bioactive compound responsible for the antibacterial effect in Euryops arabicus .
    trans-β-Terpineol
  • HY-W001084R
    Methyl 4-hydroxyphenylacetate (Standard)

    		Reference Standards Others
    Methyl 4-hydroxyphenylacetate (Standard) is the analytical standard of Methyl 4-hydroxyphenylacetate (HY-W001084). This product is intended for research and analytical applications. Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate (Standard)
  • HY-Y1083C
    Potassium sulfate, for cell culture

    Salt of lemery, for cell culture

    		 Biochemical Assay Reagents Others
    Potassium sulfate, for cell culture (Salt of lemery, for cell culture) can be used in plant cell culture and as a potassium source in media preparation, promoting cell growth and maintaining osmotic balance .
    Potassium sulfate, for cell culture
  • HY-135078
    2,5-Deoxyfructosazine

    NSC 270912

    		 DNA/RNA Synthesis Others
    2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
    2,5-Deoxyfructosazine
  • HY-W016393R
    Dihydroconiferyl alcohol (Standard)

    		Reference Standards Endogenous Metabolite Others
    Dihydroconiferyl alcohol (Standard) is an analytical standard of Dihydroconiferyl alcohol (HY-W016393). This product is intended for research and analytical applications. Dihydroconiferyl alcohol is a cell division factor. Dihydroconiferyl alcohol can be isolated from the American sycamore (Acer pseudoplatanus L.). Dihydroconiferyl alcohol inhibits the degradation of Indole-3-acetic acid (HY-18569). Dihydroconiferyl alcohol can stimulate the growth of soybean and tobacco callus tissue and synergistically enhance Indole-3-acetic acid-induced hypocotyl elongation in cucumber. Dihydroconiferyl alcohol can be used in the research of plant growth regulation .
    Dihydroconiferyl alcohol (Standard)
  • HY-34516R
    D-Ornithine hydrochloride (Standard)

    (R)-Ornithine hydrochloride (Standard)

    		 Endogenous Metabolite Bacterial Reference Standards Metabolic Disease
    D-Ornithine (hydrochloride) (Standard) is the analytical standard of D-Ornithine (hydrochloride). This product is intended for research and analytical applications. D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .
    D-Ornithine hydrochloride (Standard)
  • HY-N15076
    Herbimycin B

    		Src Antibiotic Bacterial Infection Cancer
    Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells .
    Herbimycin B
  • HY-W743781
    N-Nitrosonornicotine-d4

    (2S)-N'-Nitrosonornicotine-d4

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Cancer
    N-Nitrosonornicotine-d4 ((2S)-N'-Nitrosonornicotine-d4) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
    N-Nitrosonornicotine-d4
  • HY-W014928
    Anabasine hydrochloride

    (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride

    		 nAChR Neurological Disease
    Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
    Anabasine hydrochloride
  • HY-W777675
    2,5-Deoxyfructosazine-13C4

    NSC 270912-13C4

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Others
    2,5-Deoxyfructosazine- 13C4 (NSC 270912- 13C4) is the 13C-labeled 2,5-Deoxyfructosazine (HY-135078). 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
    2,5-Deoxyfructosazine-13C4
  • HY-B1532R
    Anabasine (Standard)

    (S)-Anabasine (Standard); (+)-Anabasine (Standard)

    		 Reference Standards nAChR Neurological Disease
    Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine (Standard)
  • HY-B1972R
    Napropamide (Standard)

    Napropamid (Standard)

    		 Herbicide Reference Standards DNA/RNA Synthesis Others
    Napropamide (Standard) (Napropamid (Standard)) is the analytical standard of Napropamide (HY-B1972). This product is intended for research and analytical applications. Napropamide (Napropamid) is an amide herbicide that can be used to control weeds in fruits, vegetables, tobacco, and ornamental plants. Napropamide mainly exerts its effect by inhibiting DNA synthesis and cell division. Napropamide has moderate to high persistence in the field, with a half-life of 24-131 days, and is prone to photodegradation.
    Napropamide (Standard)
  • HY-41404R
    Piperonylic acid (Standard)

    2H-1,3-benzodioxole-5-carboxylic acid (Standard)

    		 Cytochrome P450 Interleukin Related EGFR IGF-1R Reference Standards Infection Others Cancer
    Piperonylic acid (Standard) is the analytical standard of Piperonylic acid. This product is intended for research and analytical applications. Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities .
    Piperonylic acid (Standard)
  • HY-W724357
    Napropamide-d10

    Napropamid-d10

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Herbicide Others
    Napropamide-d10 (Napropamid-d10) is the deuterium labeled Napropamide (HY-B1972). Napropamide (Napropamid) is an amide herbicide that can be used to control weeds in fruits, vegetables, tobacco, and ornamental plants. Napropamide mainly exerts its effect by inhibiting DNA synthesis and cell division. Napropamide has moderate to high persistence in the field, with a half-life of 24-131 days, and is prone to photodegradation .
    Napropamide-d10
  • HY-N18115A
    Toosendansin A

    		Drug Derivative Cancer
    Toosendansin A is a salannin-type limonoid and cytotoxic agent found in the fruits of Melia azedarach. Toosendansin A can be used for the research of leukemia, stomach cancer, breast cancer .
    Toosendansin A
  • HY-W547534
    2,4-D ammonium

    2,4-Dichlorophenoxyacetic acid ammonium

    		 Herbicide DNA/RNA Synthesis Apoptosis Cancer
    2,4-D (2, 4-dichlorophenoxyacetic acid) ammonium is a selective herbicide that can be used for the control of broad-leaved weeds. 2,4-D ammonium can induce apoptosis. 2,4-D ammonium inhibits DNA and protein synthesis, thereby preventing normal plant growth and development .
    2,4-D ammonium

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