2,5-Deoxyfructosazine
Based on 1 Customer Validation
2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
For research use only. We do not sell to patients.
- Purity: 98.05%
- CAS No.: 17460-13-8
- Formula: C12H20N2O7
- Molecular Weight:304.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 17460-13-8
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Appearance Solid
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Molecular Weight 304.30
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Formula C12H20N2O7
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Color Light yellow to brown
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SMILES
O[C@H](C1=NC=C(C[C@H](O)[C@H](O)CO)N=C1)[C@H](O)[C@H](O)CO
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Synonyms
NSC 270912
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 12.5 mg/mL (41.08 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.2862 mL | 16.4312 mL | 32.8623 mL | 82.1558 mL |
| 5 mM | 0.6572 mL | 3.2862 mL | 6.5725 mL | 16.4312 mL | |
| 10 mM | 0.3286 mL | 1.6431 mL | 3.2862 mL | 8.2156 mL | |
| 15 mM | 0.2191 mL | 1.0954 mL | 2.1908 mL | 5.4771 mL | |
| 20 mM | 0.1643 mL | 0.8216 mL | 1.6431 mL | 4.1078 mL | |
| 25 mM | 0.1314 mL | 0.6572 mL | 1.3145 mL | 3.2862 mL | |
| 30 mM | 0.1095 mL | 0.5477 mL | 1.0954 mL | 2.7385 mL | |
| 40 mM | 0.0822 mL | 0.4108 mL | 0.8216 mL | 2.0539 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.