Anabasine hydrochloride
Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM).
For research use only. We do not sell to patients.
- CAS No.: 53912-89-3
- Formula: C10H15ClN2
- Molecular Weight:198.69
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
nAChR[1]
Chemical Information
-
CAS No. 53912-89-3
-
Molecular Weight 198.69
-
Formula C10H15ClN2
-
SMILES
[H]Cl.C1([C@H]2NCCCC2)=CC=CN=C1
-
Synonyms
(S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Green BT, et, al. Actions of piperidine alkaloid teratogens at fetal nicotinic acetylcholine receptors. Neurotoxicol Teratol. May-Jun 2010; 32(3): 383-90. [Content Brief]
[2]. Palmer-Young EC, et, al. Context-dependent medicinal effects of anabasine and infection-dependent toxicity in bumble bees. PLoS One. 2017 Aug 23; 12(8): e0183729. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)