D-Ornithine hydrochloride
Based on 1 Customer Validation
D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 16682-12-5
- Formula: C5H13ClN2O2
- Molecular Weight:168.62
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Human Endogenous Metabolite |
D-Ornithine (1-10 mM, 24 h) hydrochloride results in a selective up-regulation of L-arginine (HY-N0455) in tobacco cells[2].
D-Ornithine (5 mM) hydrochloride promotes the insertion of pyrroline-carboxy-lysine (Pcl) into proteins in E. coli and HEK293 cells containing the pyl genes[3].
D-Ornithine (1-10 mM) hydrochloride can stimulate production of spermidine and spermine in tobacco cells[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16682-12-5
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Appearance Solid
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Molecular Weight 168.62
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Formula C5H13ClN2O2
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Color White to off-white
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SMILES
N[C@H](CCCN)C(O)=O.[H]Cl
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Synonyms
(R)-Ornithine hydrochloride
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (593.05 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (593.05 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[2]. Cellitti SE, et al. D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine. Nat Chem Biol. 2011 Apr 27;7(8):528-30. [Content Brief]
[3]. Gholami M, et al. Selective regulation of nicotine and polyamines biosynthesis in tobacco cells by enantiomers of ornithine. Chirality. 2013 Jan;25(1):22-7. [Content Brief]
[4]. DUC-NGUYEN H, et al. D-ORNITHINE AS A CONSTITUENT OF A BACTERIAL CELL WALL. J Biol Chem. 1964 Oct;239:3372-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.9305 mL | 29.6525 mL | 59.3049 mL | 148.2624 mL |
| 5 mM | 1.1861 mL | 5.9305 mL | 11.8610 mL | 29.6525 mL | |
| 10 mM | 0.5930 mL | 2.9652 mL | 5.9305 mL | 14.8262 mL | |
| 15 mM | 0.3954 mL | 1.9768 mL | 3.9537 mL | 9.8842 mL | |
| 20 mM | 0.2965 mL | 1.4826 mL | 2.9652 mL | 7.4131 mL | |
| 25 mM | 0.2372 mL | 1.1861 mL | 2.3722 mL | 5.9305 mL | |
| 30 mM | 0.1977 mL | 0.9884 mL | 1.9768 mL | 4.9421 mL | |
| 40 mM | 0.1483 mL | 0.7413 mL | 1.4826 mL | 3.7066 mL | |
| 50 mM | 0.1186 mL | 0.5930 mL | 1.1861 mL | 2.9652 mL | |
| 60 mM | 0.0988 mL | 0.4942 mL | 0.9884 mL | 2.4710 mL | |
| 80 mM | 0.0741 mL | 0.3707 mL | 0.7413 mL | 1.8533 mL | |
| 100 mM | 0.0593 mL | 0.2965 mL | 0.5930 mL | 1.4826 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Ornithine hydrochloride Related Classifications
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