2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. L-Proline

L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

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L-Proline Chemical Structure

L-Proline Chemical Structure

CAS No. : 147-85-3

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
500 mg USD 50 In-stock
5 g USD 60 In-stock
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50 g   Get quote  

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Based on 2 publication(s) in Google Scholar

Other Forms of L-Proline:

L-Proline Related Antibodies

Top Publications Citing Use of Products

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  • Purity & Documentation

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Description

L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

IC50 & Target

Human Endogenous Metabolite

 

Microbial Metabolite

 

Molecular Weight

115.13

Formula

C5H9NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H]1NCCC1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (434.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.6858 mL 43.4292 mL 86.8583 mL
5 mM 1.7372 mL 8.6858 mL 17.3717 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (868.58 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.98%

COA (249 KB) HNMR (128 KB) LCMS (92 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.6858 mL 43.4292 mL 86.8583 mL 217.1458 mL
5 mM 1.7372 mL 8.6858 mL 17.3717 mL 43.4292 mL
10 mM 0.8686 mL 4.3429 mL 8.6858 mL 21.7146 mL
15 mM 0.5791 mL 2.8953 mL 5.7906 mL 14.4764 mL
20 mM 0.4343 mL 2.1715 mL 4.3429 mL 10.8573 mL
25 mM 0.3474 mL 1.7372 mL 3.4743 mL 8.6858 mL
30 mM 0.2895 mL 1.4476 mL 2.8953 mL 7.2382 mL
40 mM 0.2171 mL 1.0857 mL 2.1715 mL 5.4286 mL
50 mM 0.1737 mL 0.8686 mL 1.7372 mL 4.3429 mL
60 mM 0.1448 mL 0.7238 mL 1.4476 mL 3.6191 mL
80 mM 0.1086 mL 0.5429 mL 1.0857 mL 2.7143 mL
100 mM 0.0869 mL 0.4343 mL 0.8686 mL 2.1715 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Proline Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Proline147-85-3Endogenous MetaboliteInhibitorinhibitorinhibit

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