(R)-pyrrolidine-2-carboxylic acid
Based on 1 Customer Validation
(R)-pyrrolidine-2-carboxylic acid ((+)-(R)-Proline) is a proline isomer that exhibits high renal and hepatotoxicity in rats. (R)-pyrrolidine-2-carboxylic acid can be used to study amino acid metabolism and toxicity mechanisms.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 344-25-2
- Formula: C5H9NO2
- Molecular Weight:115.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-42068
(-)-Aspartic acid
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HY-Y0378
D-Leucine
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HY-75087R
(R)-pyrrolidine-2-carboxylic acid (Standard)
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HY-Y0378R
D-Leucine (Standard)
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HY-100805
D-Glutamic acid
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HY-Y0337
L-Cysteine
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HY-N0486
L-Leucine
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HY-100805R
D-Glutamic acid (Standard)
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HY-100808
D-Serine
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HY-41700
D-Alanine
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HY-Y0079
D-Phenylalanine
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HY-N0486R
L-Leucine (Standard)
All Endogenous Metabolite Isoforms
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Biological Activity
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Microbial Metabolite |
Human Endogenous Metabolite |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley rats[2]
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Dosage:50 mg/kg
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Administration:Oral gavage (p.o.)
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Result:Increased the levels of GOT, GPT, alkaline phosphatase, γ-glutamic oxaloacetate aminotransferase, lactate dehydrogenase, aspartate aminotransferase, and creatinine in serum.
Chemical Information
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CAS No. 344-25-2
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Appearance Solid
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Molecular Weight 115.13
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Formula C5H9NO2
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Color White to off-white
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SMILES
O=C(O)[C@@H]1NCCC1
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Synonyms
(+)-(R)-Proline; (R)-(+)-Proline; (R)-2-Carboxypyrrolidine; (R)-Proline
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 25 mg/mL (217.15 mM; Need ultrasonic)
DMSO : 2.78 mg/mL (24.15 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 12.5 mg/mL (108.57 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 8.6858 mL | 43.4292 mL | 86.8583 mL | 217.1458 mL |
| 5 mM | 1.7372 mL | 8.6858 mL | 17.3717 mL | 43.4292 mL | |
| 10 mM | 0.8686 mL | 4.3429 mL | 8.6858 mL | 21.7146 mL | |
| 15 mM | 0.5791 mL | 2.8953 mL | 5.7906 mL | 14.4764 mL | |
| 20 mM | 0.4343 mL | 2.1715 mL | 4.3429 mL | 10.8573 mL | |
| H2O | 25 mM | 0.3474 mL | 1.7372 mL | 3.4743 mL | 8.6858 mL |
| 30 mM | 0.2895 mL | 1.4476 mL | 2.8953 mL | 7.2382 mL | |
| 40 mM | 0.2171 mL | 1.0857 mL | 2.1715 mL | 5.4286 mL | |
| 50 mM | 0.1737 mL | 0.8686 mL | 1.7372 mL | 4.3429 mL | |
| 60 mM | 0.1448 mL | 0.7238 mL | 1.4476 mL | 3.6191 mL | |
| 80 mM | 0.1086 mL | 0.5429 mL | 1.0857 mL | 2.7143 mL | |
| 100 mM | 0.0869 mL | 0.4343 mL | 0.8686 mL | 2.1715 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
(R)-pyrrolidine-2-carboxylic acid Related Classifications
HY-75087 Related Classifications
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