1. (-)-Aspartic acid

(-)-Aspartic acid  (Synonyms: (R)-Aspartic acid; D-(-)-Aspartic acid)

Cat. No.: HY-42068 Purity: ≥98.0%
COA Handling Instructions

(-)-Aspartic acid is an endogenous NMDA receptor agonist.

For research use only. We do not sell to patients.

(-)-Aspartic acid Chemical Structure

(-)-Aspartic acid Chemical Structure

CAS No. : 1783-96-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
500 mg USD 50 In-stock
5 g USD 60 In-stock
25 g USD 150 In-stock
50 g USD 225 In-stock
> 100 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

(-)-Aspartic acid is an endogenous NMDA receptor agonist.

IC50 & Target

NMDA receptor

Molecular Weight

133.10

Formula

C4H7NO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N[C@@H](C(O)=O)CC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 7.69 mg/mL (57.78 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.5131 mL 37.5657 mL 75.1315 mL
5 mM 1.5026 mL 7.5131 mL 15.0263 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 2 mg/mL (15.03 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.5131 mL 37.5657 mL 75.1315 mL 187.8287 mL
5 mM 1.5026 mL 7.5131 mL 15.0263 mL 37.5657 mL
10 mM 0.7513 mL 3.7566 mL 7.5131 mL 18.7829 mL
15 mM 0.5009 mL 2.5044 mL 5.0088 mL 12.5219 mL
20 mM 0.3757 mL 1.8783 mL 3.7566 mL 9.3914 mL
25 mM 0.3005 mL 1.5026 mL 3.0053 mL 7.5131 mL
30 mM 0.2504 mL 1.2522 mL 2.5044 mL 6.2610 mL
40 mM 0.1878 mL 0.9391 mL 1.8783 mL 4.6957 mL
50 mM 0.1503 mL 0.7513 mL 1.5026 mL 3.7566 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(-)-Aspartic acid
Cat. No.:
HY-42068
Quantity:
MCE Japan Authorized Agent: