2. Anti-infection
  3. Bacterial Parasite Antibiotic
  4. Sulfadiazine sodium

Sulfadiazine sodium 

Cat. No.: HY-B0273A Purity: ≥98.0%
COA Handling Instructions

Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research.

For research use only. We do not sell to patients.

Sulfadiazine sodium Chemical Structure

Sulfadiazine sodium Chemical Structure

CAS No. : 547-32-0

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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
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Solid
500 mg USD 50 In-stock
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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Sulfadiazine sodium:

Sulfadiazine sodium Related Antibodies

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Description

Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research[1][2].

IC50 & Target

Toxoplasma

 

In Vivo

In this study, the effectiveness of Sulfadiazine sodium and Pyrimetamine for the treatment of mice during acute infection with different atypical T. gondii strains was evaluated. Swiss mice were infected with seven T. gondii strainsl. The infected mice were treated with 10-640 mg/kg per day of Sulfadiazine sodium, 3-200 mg/kg per day of Pyrimetamine, or a combination of both drugs with a lower dosage. A descriptive analysis was used to assess the association between susceptibility to sodium and/or Pyrimetamine and the genotype. The TgCTBr4 and TgCTBr17 strains (genotype 108) presented lower susceptibility to sodium or Pyrimetamine treatment. The TgCTBr1 and TgCTBr25 strains (genotype 206) presented similar susceptibility to PYR but not sodium treatment. The TgCTBr9 strain (genotype 11) was the only strain with high susceptibility to treatment with both drugs [1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

272.26

Appearance

Solid

Formula

C10H9N4NaO2S
CAS No.
SMILES

O=S(C1=CC=C(N)C=C1)(N([Na])C2=NC=CC=N2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (459.12 mM; Need ultrasonic)

H2O : 100 mg/mL (367.30 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6730 mL 18.3648 mL 36.7296 mL
5 mM 0.7346 mL 3.6730 mL 7.3459 mL
10 mM 0.3673 mL 1.8365 mL 3.6730 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (7.64 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (7.64 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (7.64 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Sulfadiazine sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Sulfadiazine547-32-0BacterialParasiteAntibioticsulfonamideantibioticveterinarypigtoxoplasmosisantimalarialInhibitorinhibitorinhibit

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