Sulfadiazine-d4
Based on 1 Customer Validation
Sulfadiazine-d4 is a deuterium labeled Sulfadiazine (HY-B0273). Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection.
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 1020719-78-1
- Formula: C10H6D4N4O2S
- Molecular Weight:254.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1020719-78-1
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Unlabeled Cas 68-35-9
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Appearance Solid
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Molecular Weight 254.30
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Formula C10H6D4N4O2S
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Color Off-white to light brown
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SMILES
O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC=CC=N2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 50 mg/mL (196.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Kucan JO, et al. Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers. J Am Geriatr Soc. 1981 May;29(5):232-5. [Content Brief]
[2]. Kabha M, et al. Sulfadiazine-Induced Obstructive Nephropathy Presenting with Upper Urinary TractExtravasation. J Endourol Case Rep. 2016 Sep 1;2(1):159-161. eCollection 2016. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9324 mL | 19.6618 mL | 39.3236 mL | 98.3091 mL |
| 5 mM | 0.7865 mL | 3.9324 mL | 7.8647 mL | 19.6618 mL | |
| 10 mM | 0.3932 mL | 1.9662 mL | 3.9324 mL | 9.8309 mL | |
| 15 mM | 0.2622 mL | 1.3108 mL | 2.6216 mL | 6.5539 mL | |
| 20 mM | 0.1966 mL | 0.9831 mL | 1.9662 mL | 4.9155 mL | |
| 25 mM | 0.1573 mL | 0.7865 mL | 1.5729 mL | 3.9324 mL | |
| 30 mM | 0.1311 mL | 0.6554 mL | 1.3108 mL | 3.2770 mL | |
| 40 mM | 0.0983 mL | 0.4915 mL | 0.9831 mL | 2.4577 mL | |
| 50 mM | 0.0786 mL | 0.3932 mL | 0.7865 mL | 1.9662 mL | |
| 60 mM | 0.0655 mL | 0.3277 mL | 0.6554 mL | 1.6385 mL | |
| 80 mM | 0.0492 mL | 0.2458 mL | 0.4915 mL | 1.2289 mL | |
| 100 mM | 0.0393 mL | 0.1966 mL | 0.3932 mL | 0.9831 mL |