1020719-78-1
Chemical Structure
Sulfadiazine-d4
- CAS No.: 1020719-78-1
- Formula:C10H6D4N4O2S
- Molecular Weight:254.30
IUPAC Name: 4-amino-N-(pyrimidin-2-yl)benzene-2,3,5,6-d4-sulfonamide
InChIKey: SEEPANYCNGTZFQ-QFFDRWTDSA-N
SMILES: O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC=CC=N2)=O
Biological Activity: Sulfadiazine-d4 is a deuterium labeled Sulfadiazine (HY-B0273). Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection[1][2][3][4].
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Sulfadiazine-d4 | 99.31% | Sulfadiazine-d4 is a deuterium labeled Sulfadiazine (HY-B0273). Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection. | ||||||||||||||||||||
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Sulfadiazine (Standard) | 99.84% | Sulfadiazine (Standard) is the analytical standard of Sulfadiazine (HY-B0273). This product is intended for research and analytical applications. Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection. | ||||||||||||||||||||
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Sulfadiazine-13C6 | 99.18% | Sulfadiazine-13C6 is a labeled Sulfadiazine (HY-B0273). Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection. | ||||||||||||||||||||
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Sulfadiazine | 99.89% | Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection. | ||||||||||||||||||||
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Sulfadiazine 100 µg/mL in methanol | Sulfadiazine 100 µg/mL in methanol is an orally active sulfonamide antibiotic. Sulfadiazine 100 µg/mL in methanol competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine 100 µg/mL in methanol persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine 100 µg/mL in methanol targets Toxoplasma gondii DHPS enzyme. Sulfadiazine 100 µg/mL in methanol can be used for the research of congenital toxoplasmosis and bacterial infection. | |||||||||||||||||||||
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- [1]. Kucan JO, et al. Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers. J Am Geriatr Soc. 1981 May;29(5):232-5. [Content Brief]
- [2]. Kabha M, et al. Sulfadiazine-Induced Obstructive Nephropathy Presenting with Upper Urinary TractExtravasation. J Endourol Case Rep. 2016 Sep 1;2(1):159-161. eCollection 2016. [Content Brief]