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Results for "

anti-histamine agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (6) Apoptosis (4) Cholinesterase (ChE) (1) Cytochrome P450 (4) Dopamine Receptor (7) Dopamine Transporter (1) Endogenous Metabolite (5) Environmental Pollutants (2) Filovirus (3) Histamine Receptor (52) Isotope-Labeled Compounds (11) mAChR (5) mGluR (3) P-glycoprotein (1) Parasite (3) Photosensitizer (5) Potassium Channel (2) Reference Standards (13) SARS-CoV (3) Serotonin Transporter (1) Sigma Receptor (1)
By Research Areas:	Cancer (19) Cardiovascular Disease (1) Endocrinology (20) Infection (4) Inflammation/Immunology (32) Metabolic Disease (1) Neurological Disease (29)

By Targets:

5-HT Receptor (6)

Apoptosis (4)

Cholinesterase (ChE) (1)

Cytochrome P450 (4)

Dopamine Receptor (7)

Dopamine Transporter (1)

Endogenous Metabolite (5)

Environmental Pollutants (2)

Filovirus (3)

Histamine Receptor (52)

Isotope-Labeled Compounds (11)

mAChR (5)

mGluR (3)

P-glycoprotein (1)

Parasite (3)

Photosensitizer (5)

Potassium Channel (2)

Reference Standards (13)

SARS-CoV (3)

Serotonin Transporter (1)

Sigma Receptor (1)

By Research Areas:

Cancer (19)

Cardiovascular Disease (1)

Endocrinology (20)

Infection (4)

Inflammation/Immunology (32)

Metabolic Disease (1)

Neurological Disease (29)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Nom du produit	Target	Áreas de investigación	Chemical Structure

HY-12532

Astemizole Maximum Cited Publications 8 Publications Verification R 43512	Histamine Receptor Potassium Channel	Inflammation/Immunology Endocrinology
Astemizole (R 43512), a second-generation antihistamine agent to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC₅₀ of 4 nM. Astemizole also shows potent hERG K ⁺ channel blocking activity with an IC₅₀ of 0.9 nM. Astemizole has antipruritic effects .

HY-B0520A

Benztropine mesylate 5 Publications Verification Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate	Dopamine Receptor mAChR Histamine Receptor	Infection Neurological Disease Metabolic Disease Cancer
Benztropine mesylate (Benzatropine mesylate) is an orally active and BBB-permeable centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0349

Meclizine dihydrochloride 4 Publications Verification Meclozine dihydrochloride	Histamine Receptor Apoptosis	Neurological Disease Endocrinology Cancer
Meclizine (Meclozine) dihydrochloride, an *antihistamine, reversibly inhibits the interaction of histamine* at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR .

HY-B0548

Hydroxyzine 1 Publications Verification	Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine, a benzodiazepine *antihistamine* agent, acts as an orally active *histamine H1-receptor* and serotonin antagonist. Hydroxyzine has anxiolytic effect and can be used for the research of generalised anxiety disorder .

HY-W010841

Levocetirizine dihydrochloride 2 Publications Verification (R)-Cetirizine dihydrochloride	Histamine Receptor	Inflammation/Immunology Endocrinology Cancer
Levocetirizine dihydrochloride ((R)-Cetirizine dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Levocetirizine dihydrochloride is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine dihydrochloride has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-Y0546

Benzophenone 1 Publications Verification	Environmental Pollutants Endogenous Metabolite Photosensitizer	Cancer
Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

HY-B0548A

Hydroxyzine dihydrochloride 1 Publications Verification	Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine dihydrochloride, a benzodiazepine *antihistamine* agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .

HY-B0814

Levocetirizine 2 Publications Verification (R)-Cetirizine	Histamine Receptor	Inflammation/Immunology Endocrinology Cancer
Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-B0970

Diphenylpyraline hydrochloride 4-Diphenylmethoxy-1-methylpiperidine hydrochloride	Histamine Receptor	Neurological Disease Endocrinology
Diphenylpyraline hydrochloride is a potent histamine H₁?receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.

HY-B0520

Benztropine 5 Publications Verification Benzatropine; Benzotropine	Dopamine Receptor mAChR Histamine Receptor	Cancer
Benztropine (Benzatropine; Benzotropine) is an orally active and BBB-permeable centrally acting anticholinergic agent that can be used for Parkinson's disease research . Benztropine is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B1483

Methapyrilene hydrochloride Thenylpyramine hydrochloride	Environmental Pollutants Histamine Receptor	Inflammation/Immunology
Methapyrilene (Thenylpyramine) hydrochloride is an orally active H1-receptor antihistamine and an anticholinergic agent of the pyridine chemical class. Methapyrilene hydrochloride has hepatotoxicity and can be used as a hepatotoxin that cause periportal hepatic necrosis in vivo

HY-B1607

Chlorphenoxamine 1 Publications Verification	Histamine Receptor SARS-CoV Filovirus Parasite	Infection Neurological Disease Inflammation/Immunology
Chlorphenoxamine, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC₅₀s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease .

HY-136587

Oxomemazine	Histamine Receptor mGluR	Inflammation/Immunology
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (K_i= 84 nM, M1 receptor) and low (K_i= 1.65 μM, M2 receptor) affinity sites. Oxomemazine is an antihistamine and anticholinergic agent used for the study of cough treatment. Oxomemazine is protective against anaphylactic microshock in guinea pigs .

HY-B1101A

Pimethixene maleate Pimetixene maleate	5-HT Receptor Histamine Receptor	Neurological Disease Endocrinology
Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT_1A, 5-HT_2A, 5-HT_2B, 5-HT_2C, histamine H₁, dopamine D₂ and D_4.4 as well as muscarinic M₁ and M₂ receptors, with pK_is of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively .

HY-B0801S

Fexofenadine-d6 2 Publications Verification MDL-16455-d₆; Terfenadine carboxylate-d₆	Histamine Receptor	Inflammation/Immunology Endocrinology
Fexofenadine-d₆ (MDL-16455-d₆) is deuterium labeled Fexofenadine, which is an antihistamine pharmaceutical agent.

HY-U00051

Propiomazine	Histamine Receptor Dopamine Receptor	Neurological Disease
Propiomazine is an orally active antihistamine agent. Propiomazine is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia .

HY-Y0546S

Benzophenone-d10	Isotope-Labeled Compounds Endogenous Metabolite Photosensitizer	Cancer
Benzophenone-d₁₀ is the deuterium labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

HY-N7293

Bakkenolide D	Histamine Receptor	Inflammation/Immunology
Bakkenolide D is a sesquiterpene lactone. Bakkenolide D is the major component of Bakkenolides in Petasites tricholobus. Bakkenolide D exhibits anti-allergic and antihistamine activities, and can be used in studies related to allergic rhinitis .

HY-B1733

Phenyltoloxamine Bistrimin; Histionex	Histamine Receptor Sigma Receptor Cytochrome P450	Neurological Disease Inflammation/Immunology
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (K_i: 160 nM) .

HY-W010841R

Levocetirizine dihydrochloride (Standard) (R)-Cetirizine dihydrochloride (Standard)	Reference Standards Histamine Receptor	Inflammation/Immunology Endocrinology
Levocetirizine (dihydrochloride) (Standard) is the analytical standard of Levocetirizine (dihydrochloride). This product is intended for research and analytical applications. Levocetirizine dihydrochloride ((R)-Cetirizine dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Levocetirizine dihydrochloride is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine dihydrochloride has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-B0814R

Levocetirizine (Standard) (R)-Cetirizine (Standard)	Histamine Receptor Reference Standards	Inflammation/Immunology Endocrinology Cancer
Levocetirizine (Standard) is the analytical standard of Levocetirizine. This product is intended for research and analytical applications. Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-B0349A

Meclizine Meclozine	Histamine Receptor Apoptosis	Neurological Disease Inflammation/Immunology
Meclizine (Meclozine), an *antihistamine, reversibly inhibits the interaction of histamine* at the H1 receptors. Meclizine is a member of the piperazine class of H1 antagonists. Meclizine is an effective anti-motion sickness agent. Meclizine crosses the blood–brain barrier. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR. Meclizine can be used for the research of polyQ toxicity disorders, such as Huntington's disease .

HY-B0814S1

Levocetirizine-d4 (R)-Cetirizine-d₄	Isotope-Labeled Compounds	Inflammation/Immunology
Levocetirizine-d₄ ((R)-Cetirizine-d₄) is the deuterium-labeled Levocetirizine (HY-B0814) . Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-Y0546S2

Benzophenone-13C	Isotope-Labeled Compounds Endogenous Metabolite Photosensitizer	Cancer
Benzophenone- ¹³C is the ¹³C labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

HY-B1101

Pimethixene Pimetixene	5-HT Receptor Histamine Receptor	Neurological Disease Endocrinology
Pimethixene is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene is a highly potent antagonist of 5-HT_1A, 5-HT_2A, 5-HT_2B, 5-HT_2C, histamine H₁, dopamine D₂ and D_4.4 as well as muscarinic M₁ and M₂ receptors, with pK_is of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively .

HY-101678

Alinastine	Histamine Receptor	Inflammation/Immunology
Alinastine is a new antihistamine agent .

HY-B0548AS1

Hydroxyzine-d4' dihydrochloride Vistaril-d4' dihydrochloride; Atarax-d4' dihydrochloride	Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine-d₄ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine?H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .

HY-176248

Dimephosphon	Histamine Receptor Serotonin Transporter	Neurological Disease Inflammation/Immunology
Dimephosphon is an anti-inflammatory agent with *antihistamine* and antiserotonin activities. Dimephosphon helps maintain the conduction function of the spinal cord and reduces the excitability of spinal motor neurons in the area surrounding the lesion. Dimephosphon directly activates lymphatic vessel movement and improves lymphatic circulation. Dimephosphon can be used for the study of inflammatory edema, acute spinal cord injury and lymphatic circulation disorders .

HY-12532R

Astemizole (Standard) R 43512 (Standard)	Reference Standards Histamine Receptor Potassium Channel	Inflammation/Immunology Endocrinology
Astemizole (Standard) is the analytical standard of Astemizole. This product is intended for research and analytical applications. Astemizole (R 43512), a second-generation antihistamine agent to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC₅₀ of 4 nM. Astemizole also shows potent hERG K ⁺ channel blocking activity with an IC₅₀ of 0.9 nM. Astemizole has antipruritic effects .

HY-B0520AS1

Benztropine-d3 mesylate	Dopamine Receptor Histamine Receptor mAChR	Cancer
Benztropine-d₃ (mesylate) is the deuterium labeled Benztropine mesylate . Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0520AR

Benztropine mesylate (Standard) Benzatropine mesylate (Standard); Benzotropine mesylate (Standard); Benztropine methanesulfonate (Standard)	Reference Standards Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine (mesylate) (Standard) is the analytical standard of Benztropine (mesylate). This product is intended for research and analytical applications. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0520AS

Benztropine-13C,d3 mesylate	Isotope-Labeled Compounds Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine- ¹³C,d₃ (mesylate) is the ¹³C- and deuterium labeled Benztropine (mesylate). Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-A0157A

Dimethothiazine mesylate Dimetotiazine mesylate; Fonazine mesylate	Histamine Receptor 5-HT Receptor	Neurological Disease
Dimethothiazine mesylate is an orally active tricyclic anti-histamine, anti-5-HT agent with a high activity against decerebrate rigidity, a little sedative activity and little soporific action. Dimethothiazine mesylate can reduce or abolish the effects of both static and dynamic fusimotor activity on the muscle spindle in decerebrate cat. Dimethothiazine mesylate can be used to research hemicrania and spasticity .

HY-A0157B

Dimethothiazine hydrochloride Dimetotiazine hydrochloride; Fonazine hydrochloride	Histamine Receptor 5-HT Receptor	Neurological Disease
Dimethothiazine hydrochloride is an orally active tricyclic anti-histamine, anti-5-HT agent with a high activity against decerebrate rigidity, a little sedative activity and little soporific action. Dimethothiazine hydrochloride can reduce or abolish the effects of both static and dynamic fusimotor activity on the muscle spindle in decerebrate cat. Dimethothiazine hydrochloride can be used to research hemicrania and spasticity .

HY-A0157

Dimethothiazine Dimetotiazine; Fonazine	Histamine Receptor 5-HT Receptor	Neurological Disease
Dimethothiazine (Dimetotiazine; Fonazine) is an orally active tricyclic anti-histamine, anti-5-HT agent with a high activity against decerebrate rigidity, a little sedative activity and little soporific action. Dimethothiazine can reduce or abolish the effects of both static and dynamic fusimotor activity on the muscle spindle in decerebrate cat. Dimethothiazine can be used to research hemicrania and spasticity .

HY-135475

(R)-Meclizine	Histamine Receptor	Others
(R)-Meclizine is the enantiomer of Meclizine. Meclizine is an antihistamine agent .

HY-N1514R

Ganoderenic acid B (Standard)	Reference Standards P-glycoprotein	Cancer
Doxylamine (succinate) (Standard) is the analytical standard of Doxylamine (succinate). This product is intended for research and analytical applications. Doxylamine (succinate), a first generation antihistamine, is a histamine (H1) receptor antagonist. Doxylamine is also a local analgesic agent and effective hypnotic agent .

HY-101314

3-CPMT Tropine 4-chlorobenzhydryl ether hydrochloride	Dopamine Transporter	Neurological Disease
3-CPMT (Tropine 4-chlorobenzhydryl ether hydrochloride) is a potent dopamine uptake inhibitor . 3-CPMT (Tropine 4-chlorobenzhydryl ether hydrochloride) acts as a potent long-acting antihistaminic agent .

HY-13762

Tesmilifene	Cytochrome P450	Cancer
Tesmilifene is an antihistamine agent and a chemical sensitizer. Tesmilifene targets cytochrome P450, exhibits hormonal effects on DNA synthesis in MCF-7 cells, and stimulates the tumor growth in mouse/rat models. Tesmilifene overcomes multidrug resistance .

HY-123432

AHR-13268D	Histamine Receptor	Inflammation/Immunology
AHR-13268D is an oral active antiallergic and antihistaminic agent, with bioavailable approximately 88%. AHR-13268D is a potent inhibitor of histamine release from rat peritoneal mast cells, with the IC₅₀ of 0.51 nM .

HY-107431

Diphenylpyraline	Histamine Receptor	Inflammation/Immunology
Diphenylpyraline is a potent histamine H₁ receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

HY-B0548AS2

Hydroxyzine-d8 dihydrochloride	Isotope-Labeled Compounds Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine-d₈ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine?H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .

HY-B0548R

Hydroxyzine (Standard)	Reference Standards Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine (Standard) is the analytical standard of Hydroxyzine. This product is intended for research and analytical applications. Hydroxyzine, a benzodiazepine *antihistamine* agent, acts as an orally active *histamine H1-receptor* and serotonin antagonist. Hydroxyzine has anxiolytic effect and can be used for the research of generalised anxiety disorder .

HY-B0548AR

Hydroxyzine dihydrochloride (Standard)	Reference Standards Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine (dihydrochloride) (Standard) is the analytical standard of Hydroxyzine (dihydrochloride). This product is intended for research and analytical applications. Hydroxyzine dihydrochloride, a benzodiazepine *antihistamine* agent, acts as a orally active *histamine H1-receptor* and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .

HY-13762S

Tesmilifene-d4	Isotope-Labeled Compounds Cytochrome P450	Cancer
Tesmilifene-d4 is the deuterium labeled Tesmilifene (HY-13762). Tesmilifene is an antihistamine agent and a chemical sensitizer. Tesmilifene targets cytochrome P450, exhibits hormonal effects on DNA synthesis in MCF-7 cells, and stimulates the tumor growth in mouse/rat models. Tesmilifene overcomes multidrug resistance .

HY-U00051A

Propiomazine hydrochloride	Histamine Receptor	Neurological Disease
Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia .

HY-14939A

Vapitadine hydrochloride	Histamine Receptor	Inflammation/Immunology
Vapitadine hydrochloride (Compound 3a) is a selective, orally active and nonsedating antihistamine agent, which exhibits a good binding affinity with human cloned histamine H1 receptor with a K_i of 19 nM. Vapitadine hydrochloride decreases the histamine-induced lethality (ED₅₀ is 0.056-1.2 mg/kg), antagonizes the cutaneous reactions to histamine (ED₅₀ is 0.51-1.4 mg/kg) in rats .

HY-107431R

Diphenylpyraline (Standard)	Reference Standards Histamine Receptor	Inflammation/Immunology
Diphenylpyraline (Standard) is the analytical standard of Diphenylpyraline. This product is intended for research and analytical applications. Diphenylpyraline is a potent histamine H1?receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

HY-U00051AS1

(R)-Propiomazine-d6 hydrochloride	Isotope-Labeled Compounds	Neurological Disease
(R)-Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-U00051AS

Propiomazine-d6 hydrochloride	Isotope-Labeled Compounds Histamine Receptor	Neurological Disease
Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

Cat. No.	Nom du produit	Category	Target	Chemical Structure

HY-Y0546

Benzophenone 1 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Photosensitizer
Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

HY-N7293

Bakkenolide D	Structural Classification Productos naturales Valeriana jatamansi Jones Plants Valerianaceae Source Classification	Histamine Receptor
Bakkenolide D is a sesquiterpene lactone. Bakkenolide D is the major component of Bakkenolides in Petasites tricholobus. Bakkenolide D exhibits anti-allergic and antihistamine activities, and can be used in studies related to allergic rhinitis .

HY-N1514R

Ganoderenic acid B (Standard)	Triterpenes Structural Classification Human Gut Microbiota Metabolites Microorganisms Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Endogenous metabolite Source Classification	Reference Standards P-glycoprotein
Doxylamine (succinate) (Standard) is the analytical standard of Doxylamine (succinate). This product is intended for research and analytical applications. Doxylamine (succinate), a first generation antihistamine, is a histamine (H1) receptor antagonist. Doxylamine is also a local analgesic agent and effective hypnotic agent .

HY-Y0546R

Benzophenone (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Photosensitizer
Benzophenone (Standard) is the analytical standard of Benzophenone. This product is intended for research and analytical applications. Benzophenone standard is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone standard can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone standard can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone standard exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone standard exhibits estrogenic activity .

Cat. No.	Nom du produit	Chemical Structure

HY-B0801S

Fexofenadine-d6 2 Publications Verification
Fexofenadine-d₆ (MDL-16455-d₆) is deuterium labeled Fexofenadine, which is an antihistamine pharmaceutical agent.

HY-Y0546S

Benzophenone-d10

Benzophenone-d₁₀ is the deuterium labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

HY-B0814S1

Levocetirizine-d4

Levocetirizine-d₄ ((R)-Cetirizine-d₄) is the deuterium-labeled Levocetirizine (HY-B0814) . Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-Y0546S2

Benzophenone-13C

Benzophenone- ¹³C is the ¹³C labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

HY-B0548AS1

Hydroxyzine-d4' dihydrochloride
Hydroxyzine-d₄ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine?H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .

HY-B0520AS1

Benztropine-d3 mesylate

Benztropine-d₃ (mesylate) is the deuterium labeled Benztropine mesylate . Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0520AS

Benztropine-13C,d3 mesylate

Benztropine- ¹³C,d₃ (mesylate) is the ¹³C- and deuterium labeled Benztropine (mesylate). Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0548AS2

Hydroxyzine-d8 dihydrochloride
Hydroxyzine-d₈ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine?H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .

HY-13762S

Tesmilifene-d4
Tesmilifene-d4 is the deuterium labeled Tesmilifene (HY-13762). Tesmilifene is an antihistamine agent and a chemical sensitizer. Tesmilifene targets cytochrome P450, exhibits hormonal effects on DNA synthesis in MCF-7 cells, and stimulates the tumor growth in mouse/rat models. Tesmilifene overcomes multidrug resistance .

HY-U00051AS1

(R)-Propiomazine-d6 hydrochloride

(R)-Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-U00051AS

Propiomazine-d6 hydrochloride

Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-U00051AS2

(S)-Propiomazine-d6 hydrochloride

(S)-Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-B0814S

Levocetirizine-d4 dihydrochloride

Levocetirizine-d₄ (dihydrochloride) is the deuterium labeled Levocetirizine. Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[1].

HY-Y0546S1

Benzophenone-d5

Benzophenone-d₅ is the deuterium labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .

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