Vapitadine hydrochloride
Vapitadine hydrochloride (Compound 3a) is a selective, orally active and nonsedating antihistamine agent, which exhibits a good binding affinity with human cloned histamine H1 receptor with a Ki of 19 nM. Vapitadine hydrochloride decreases the histamine-induced lethality (ED50 is 0.056-1.2 mg/kg), antagonizes the cutaneous reactions to histamine (ED50 is 0.51-1.4 mg/kg) in rats.
For research use only. We do not sell to patients.
- CAS No.: 279253-83-7
- Formula: C17H22Cl2N4O
- Molecular Weight:369.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Histamine Receptor Isoforms
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Biological Activity
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Human H1 Receptor 19 nM (Ki) |
Chemical Information
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CAS No. 279253-83-7
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Molecular Weight 369.29
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Formula C17H22Cl2N4O
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SMILES
O=C(C1=CN=C2N1CCC3=CC=CC=C3C24CCNCC4)N.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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