Chlorphenoxamine hydrochloride

Cat. No.: HY-B1607A: Data Sheet Handling Instructions
FAQs
Technical Support

Chlorphenoxamine hydrochloride, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine hydrochloride inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine hydrochloride shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC₅₀s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine hydrochloride is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease.

For research use only. We do not sell to patients.

Chlorphenoxamine hydrochloride Chemical Structure

CAS No. : 562-09-4

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Chlorphenoxamine hydrochloride:

Chlorphenoxamine

Other Forms of Chlorphenoxamine hydrochloride:

Chlorphenoxamine In-stock

1 Publications Citing Use of MCE Chlorphenoxamine hydrochloride

•Antiviral Res. 2018 Sep:157:47-56. [Abstract]

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Histamine Receptor Isoform Specific Products:

View All Isoforms

H₁ Receptor H₂ Receptor H₃ Receptor H₄ Receptor Histamine Receptor

View All Filovirus Isoform Specific Products:

View All Isoforms

EBOV MARV ZEBOV

View All Parasite Isoform Specific Products:

View All Isoforms

Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

Biological Activity
Purity & Documentation
References
Customer Review

Description	Chlorphenoxamine hydrochloride, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine hydrochloride inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine hydrochloride shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC₅₀s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine hydrochloride is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease^[1]^[2]^[3]^[4]^[5].
Molecular Weight	340.29
Formula	C₁₈H₂₃Cl₂NO
CAS No.	562-09-4
SMILES	CC(C1=CC=CC=C1)(C2=CC=C(Cl)C=C2)OCCN(C)C.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. ULDALL PR, et al. Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial. Br Med J. 1961 Jun 10;1(5240):1649-52. [Content Brief] [2]. BAZEX A, et al. Trial treatment of urticaria with chlorphenoxamine. Clinique (Paris). 1963 Jul-Aug;58:447-50. [Content Brief] [3]. Schafer A, et al. Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics. Antiviral Res. 2018 Sep;157:47-56. [Content Brief] [4]. Ashraf A, et al. Novel RP-HPLC-DAD approach for simultaneous determination of chlorphenoxamine hydrochloride and caffeine with their related substances. BMC Chem. 2024;18(1):133. Published 2024 Jul 19. [Content Brief] [5]. Ashraf A, et al. Smart green spectrophotometric estimation and content uniformity testing of chlorphenoxamine HCl and caffeine in bulk forms and combined pharmaceutical formulation. Sci Rep. 2025;15(1):9482. Published 2025 Mar 19. [Content Brief]