Chlorphenoxamine hydrochloride
Based on 1 publication(s) in Google Scholar
Chlorphenoxamine hydrochloride, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine hydrochloride inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine hydrochloride shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC50s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine hydrochloride is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease.
For research use only. We do not sell to patients.
- CAS No.: 562-09-4
- Formula: C18H23Cl2NO
- Molecular Weight:340.29
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Chlorphenoxamine hydrochloride
MoreAll Histamine Receptor Isoforms
MoreAll Parasite Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 562-09-4
-
Molecular Weight 340.29
-
Formula C18H23Cl2NO
-
SMILES
CC(C1=CC=CC=C1)(C2=CC=C(Cl)C=C2)OCCN(C)C.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Antiviral Res
Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics. [Abstract]2018 Sep:157:47-56. PMID: 29981374
Purity & Documentation
References
[1]. ULDALL PR, et al. Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial. Br Med J. 1961 Jun 10;1(5240):1649-52. [Content Brief]
[2]. BAZEX A, et al. Trial treatment of urticaria with chlorphenoxamine. Clinique (Paris). 1963 Jul-Aug;58:447-50. [Content Brief]
[3]. Schafer A, et al. Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics. Antiviral Res. 2018 Sep;157:47-56. [Content Brief]
[4]. Ashraf A, et al. Novel RP-HPLC-DAD approach for simultaneous determination of chlorphenoxamine hydrochloride and caffeine with their related substances. BMC Chem. 2024;18(1):133. Published 2024 Jul 19. [Content Brief]
[5]. Ashraf A, et al. Smart green spectrophotometric estimation and content uniformity testing of chlorphenoxamine HCl and caffeine in bulk forms and combined pharmaceutical formulation. Sci Rep. 2025;15(1):9482. Published 2025 Mar 19. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlorphenoxamine hydrochloride Related Classifications
HY-B1607A Related Classifications
Powered by Bioz