Benzophenone-13C
Based on 1 Customer Validation
Benzophenone-13C is the 13C labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity.
For research use only. We do not sell to patients.
- Purity : 99.80%
- CAS No.: 32488-48-5
- Formula: C1213CH10O
- Molecular Weight:183.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 32488-48-5
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Unlabeled CAS 119-61-9
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Appearance Solid
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Molecular Weight 183.21
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Formula C1213CH10O
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Color White to off-white
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SMILES
O=[13C](C1=CC=CC=C1)C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (545.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (274 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
[1]. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Silano V, et al., Safety of benzophenone to be used as flavouring. EFSA J. 2017 Nov 14;15(11):e05013. [Content Brief]
[2]. Rhodes MC, et al., Carcinogenesis studies of benzophenone in rats and mice. Food Chem Toxicol. 2007 May;45(5):843-51. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4582 mL | 27.2911 mL | 54.5822 mL | 136.4554 mL |
| 5 mM | 1.0916 mL | 5.4582 mL | 10.9164 mL | 27.2911 mL | |
| 10 mM | 0.5458 mL | 2.7291 mL | 5.4582 mL | 13.6455 mL | |
| 15 mM | 0.3639 mL | 1.8194 mL | 3.6388 mL | 9.0970 mL | |
| 20 mM | 0.2729 mL | 1.3646 mL | 2.7291 mL | 6.8228 mL | |
| 25 mM | 0.2183 mL | 1.0916 mL | 2.1833 mL | 5.4582 mL | |
| 30 mM | 0.1819 mL | 0.9097 mL | 1.8194 mL | 4.5485 mL | |
| 40 mM | 0.1365 mL | 0.6823 mL | 1.3646 mL | 3.4114 mL | |
| 50 mM | 0.1092 mL | 0.5458 mL | 1.0916 mL | 2.7291 mL | |
| 60 mM | 0.0910 mL | 0.4549 mL | 0.9097 mL | 2.2743 mL | |
| 80 mM | 0.0682 mL | 0.3411 mL | 0.6823 mL | 1.7057 mL | |
| 100 mM | 0.0546 mL | 0.2729 mL | 0.5458 mL | 1.3646 mL |