2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor mGluR
  4. Oxomemazine

Oxomemazine 

Cat. No.: HY-136587 Purity: 99.18%
COA Handling Instructions

Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki = 84 nM, M1 receptor) and low (Ki = 1.65 μM, M2 receptor) affinity sites. Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment.

For research use only. We do not sell to patients.

Oxomemazine Chemical Structure

Oxomemazine Chemical Structure

CAS No. : 3689-50-7

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5 mg USD 38 In-stock
10 mg USD 60 In-stock
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Based on 1 publication(s) in Google Scholar

Oxomemazine Related Antibodies

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Description

Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki = 84 nM, M1 receptor) and low (Ki = 1.65 μM, M2 receptor) affinity sites[1]. Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment[2].

IC50 & Target

H1 Receptor

 

mGluR 1

84 nM (Ki)

mGluR2

1.65 μM (Ki)

Molecular Weight

330.44

Appearance

Solid

Formula

C18H22N2O2S
CAS No.
SMILES

CC(CN1C2=C(C=CC=C2)S(C3=CC=CC=C13)(=O)=O)CN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (302.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0263 mL 15.1313 mL 30.2627 mL
5 mM 0.6053 mL 3.0263 mL 6.0525 mL
10 mM 0.3026 mL 1.5131 mL 3.0263 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Oxomemazine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Oxomemazine3689-50-7Histamine ReceptormGluRMetabotropic glutamate receptorsphenothiazinehistamine H1-receptorantimuscarinicmuscarinic M1antihistamineanticholinergiccoughInhibitorinhibitorinhibit

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