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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
anti-malarial effects
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "anti-malarial effects" in MCE Product Catalog:
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47 Publications Verification
Cat. No.: HY-N0674A
CAS No.: 10605-03-5
Synonyms: 13-Methylpalmatine chloride
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34
Category:
Infection Piscidia erythrina L. Neurological Disease Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields
Target:
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Research Areas:
Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment .
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4 Cited Publications
Cat. No.: HY-N0152
CAS No.: 17912-87-7
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3 Cited Publications
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2 Cited Publications
Cat. No.: HY-W012732
CAS No.: 119-65-3
1
1 Cited Publications
Cat. No.: HY-N5029
CAS No.: 32434-44-9
Category:
Infection Alkaloids Dichroa febrifuga Lour Quinoline Alkaloids Plants Saxifragaceae Disease Research Fields
Target:
Hex is an enolase inhibitor and antimalarial agent with Ki values of 74.4 nM and 269.4 nM for ENO2 and ENO1, respectively. Hex is a NfENO and TbENO inhibitor with IC50s value of 0.14 μM and 2.1 μM, respectively. Hex has antimalarial activity against Plasmodium falciparum 3D7, Naegleria fowleri trophozoites and Plasmodium berghei ANKA strain. Hex has anti-tumor effects against intracranial tumors .
1H-pyrazole (Pyrazole) is a five-membered heterocyclic compound, and its derivatives are orally effective antimalarial and antileishmanial agents with the potential to modulate targets such as alcohol dehydrogenase and NMDA receptors. 1H-pyrazole derivatives exhibit inhibitory effects on Plasmodium berghei in infected mice and on promastigotes of Leishmania aethiopica, respectively. 1H-pyrazole can be used in research related to malaria and leishmaniasis .
Cat. No.: HY-B0094R
CAS No.: 63968-64-9
Synonyms: Qinghaosu (Standard); NSC 369397 (Standard)
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Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment .
Cat. No.: HY-P10338
CAS No.: 1423743-97-8
Target:
Research Areas:
Cat. No.: HY-B0094S
CAS No.: 176652-07-6
Synonyms: Qinghaosu-d3; NSC 369397-d3
Cat. No.: HY-174393
CAS No.: 1620442-30-9
Target:
Research Areas:
Gamhepathiopine is a thienopyrimidinone compound. Gamhepathiopine exerts antimalarial effects by targeting the Qo site of Plasmodium falciparum cytochrome b and inhibiting the activity of complex III in the electron transport chain .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
