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Quinacrine methanesulfonate

(Synonyms: Mepacrine methanesulfonate; SN-390 methanesulfonate)
9 Cited Publications
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Based on 9 publication(s) in Google Scholar

Quinacrine (Mepacrine) methanesulfonate is a potent, orally active antimalarial agent with antitumor effects in vitro and in vivo. Quinacrine dihydrochloride inhibits NF-κB and activates p53 signaling, inducing apoptosis in tumor cells.

For research use only. We do not sell to patients.

  • CAS No.: 316-05-2
  • Formula: C25H38ClN3O7S2
  • Molecular Weight:592.17
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Quinacrine methanesulfonate Chemical Structure
    Quinacrine methanesulfonate Chemical Structure
  • Experimental Validation Results for Quinacrine methanesulfonate
  • Experimental Validation Results for Quinacrine methanesulfonate
  • Experimental Validation Results for Quinacrine methanesulfonate
CAS No.: 316-05-2
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  • Cell Proliferation/Viability Assay
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  • Quinacrine methanesulfonate Chemical Structure
    Quinacrine methanesulfonate Chemical Structure
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    Quinacrine methanesulfonate purchased from MedChemExpress. Usage Cited in: J Biomed Sci. 2025 Feb 5;32(1):15. [Abstract]

    Customer Validation
     The tabulated datasheet from IC50 data showing the percent inhibition of SAUSA300 cells at 10 µM of G4-ligands (Quinacrine dihydrochloride, etc.) and their IC50 values.

  • 1/16

    Quinacrine methanesulfonate purchased from MedChemExpress. Usage Cited in: Part Fibre Toxicol. 2024 Mar 7;21(1):13. [Abstract]

    Customer Validation
     Cell viability of trophoblast cells treated with 10 μM Raptinal, 15 μM Quinacrine dihydrochloride, or 500 μg/mL PS-NPs, and co-treated with 10 μM Z-VAD-FMK for 48 h. The results showed that treatment with Raptinal, Quinacrine dihydrochloride, or PS-NPs reduced trophoblast cell viability, and co-treatment with Z-VAD-FMK rescued trophoblast cell viability.

  • 1/16

    Quinacrine methanesulfonate purchased from MedChemExpress. Usage Cited in: Pharmaceutics. 2022 Jan 12;14(1):176. [Abstract]

    Customer Validation
     Quinacrine (Mepacrine) dihydrochloride inhibited the enzymatic activities of TMPRSS2 and PLpro, with IC50 values ​​of 29.9 μM and 4.4 μM, respectively.

  • Quinacrine methanesulfonate