1. Anti-infection Metabolic Enzyme/Protease
  2. Bacterial Endogenous Metabolite Parasite
  3. Ambigol C

Ambigol C is an ambigol, Antibacterial agent and Antimalarial agent. Ambigol C is isolated from Fischerella ambigua 108b. Ambigol C exhibits selective antibacterial activity against Gram-positive Staphylococcus aureus strains (including MRSA) with MIC values of 0.98-3.91 μg/mL. Ambigol C also shows potent antibacterial activity against B. megaterium, and possesses weak antimalarial and trypanocidal effects. Ambigol C can be used in the research of bacterial infections, plasmodial infections and trypanosomal infections.

For research use only. We do not sell to patients.

Ambigol C

Ambigol C Chemical Structure

CAS No. : 850655-31-1

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Description

Ambigol C is an ambigol, Antibacterial agent and Antimalarial agent. Ambigol C is isolated from Fischerella ambigua 108b. Ambigol C exhibits selective antibacterial activity against Gram-positive Staphylococcus aureus strains (including MRSA) with MIC values of 0.98-3.91 μg/mL. Ambigol C also shows potent antibacterial activity against B. megaterium, and possesses weak antimalarial and trypanocidal effects. Ambigol C can be used in the research of bacterial infections, plasmodial infections and trypanosomal infections[1].

IC50 & Target[1]

Microbial Metabolite

 

Trypanosoma

 

Plasmodium

 

In Vitro

Ambigol C (24 h for antibacterial/antimycotic, 48 h for cytotoxicity) displays selective antibacterial activity against Gram-positive Staphylococcus aureus strains (including MRSA) with MIC values of 0.98-3.91 μg/mL, no activity against Escherichia coli or Candida albicans, and an IC50 of 40 μg/mL against MRC-5 human lung fibroblasts[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

484.97

Formula

C18H8Cl6O3

CAS No.
SMILES

ClC1=CC=C(C(Cl)=C1)OC2=C(Cl)C(O)=C(Cl)C(OC3=CC=C(C=C3Cl)Cl)=C2

Structure Classification
Initial Source

Fischerella ambigua

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ambigol C
Cat. No.:
HY-N18878
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