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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
cyclization reaction
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "cyclization reaction" in MCE Product Catalog:
10
Target:
7
7 Cited Publications
Synonyms: Acetyl-CoA trisodium
7
7 Cited Publications
Synonyms: Acetyl-CoA lithium
6
6 Cited Publications
Cat. No.: HY-W013636
CAS No.: 328-50-7
Synonyms: Alpha-Ketoglutaric acid; 2-Oxoglutaric acid
Category:
Anti-aging Endocrine diseases Endogenous metabolite Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Disease Research Fields
Target:
6
6 Cited Publications
Cat. No.: HY-W013636A
CAS No.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium
Target:
6
6 Cited Publications
Cat. No.: HY-W013636B
CAS No.: 71686-01-6
Target:
6
6 Cited Publications
Cat. No.: HY-W013636C
CAS No.: 997-43-3
Synonyms: Alpha-Ketoglutaric acid potassium
1
1 Cited Publications
Category:
Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
1
Category:
1
Research Areas:
Aspartate aminotransferase (EC 2.6.1.1), Genetically engineered bacteria is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Genetically engineered bacteria comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Genetically engineered bacteria also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Genetically engineered bacteria is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers .
Cat. No.: HY-Y1703
CAS No.: 148893-10-1
Target:
Research Areas:
HATU is a third-generation uronium salt peptide coupling reagent. HATU increases the rate of peptide coupling reactions, activates amino acids, promotes peptide bond formation in both solution-phase and solid-phase synthesis, and also facilitates peptide assembly, fragment coupling, and linear peptide cyclization. HATU can promote the N-acylation of chitosan to generate amide-linked cationic derivatives with a controllable degree of substitution. HATU is commonly used in amine acylation reactions .
Research Areas:
DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic sterically hindered amidine with strong basicity, which possesses multiple properties such as nucleophilicity and coordination ability. DBU is prone to hydrolysis and can undergo addition, substitution, cyclization and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst .
Cat. No.: HY-W013636S
CAS No.: 161096-83-9
Synonyms: Alpha-Ketoglutaric acid-13C5
Cat. No.: HY-W012185
CAS No.: 90-39-1
Synonyms: (-)-Lupinidine
Category:
Alkaloids Piperidine Alkaloids Leguminosae Other Diseases Plants Disease Research Fields Lupinus albus Linn.
Target:
Synonyms: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Acyl coenzyme A synthetase (ACS), namely acetyl coenzyme A synthetase, is often used in biochemical research. Acyl coenzyme A synthetase can catalyze the activation of fatty acids by coenzyme A through a two-step thioesterification reaction to produce acyl coenzyme A, and then participate in a variety of anabolic and catabolic lipid metabolism pathways, and participate in the TCA cycle in aerobic respiration .
Cat. No.: HY-114293A
CAS No.: 75520-41-1
Synonyms: Acetyl-CoA trilithium
Cat. No.: HY-W105310A
CAS No.: 14379-00-1
Synonyms: Nacr
Croconic acid disodium (Nacr) is a lysine crotonylation (Kcr) activator and electroactive material. Croconic acid disodium reduces the expression of HDAC2, HDAC3, SIRT1, and SIRT3, and increases the expression of EP300, CITED1, ACSS2, DPF2, CDYL, MLLT3, and YEATS2. Croconic acid disodium elevates intracellular crotonyl-CoA content and global histone lysine crotonylation levels. Croconic acid disodium promotes the growth of bovine fibroblasts, regulates cell cycle progression, and inhibits bovine fibroblast apoptosis (apoptosis). Croconic acid disodium improves the blastocyst development efficiency of bovine somatic cell nuclear transfer embryos. Croconic acid disodium undergoes reversible lithium intercalation/deintercalation reactions via sodium-lithium ion exchange. Croconic acid disodium is applicable to research related to cell growth promotion .
Target:
Research Areas:
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
