HATU
Based on 1 Customer Validation
HATU is a third-generation uronium salt peptide coupling reagent. HATU increases the rate of peptide coupling reactions, activates amino acids, promotes peptide bond formation in both solution-phase and solid-phase synthesis, and also facilitates peptide assembly, fragment coupling, and linear peptide cyclization. HATU can promote the N-acylation of chitosan to generate amide-linked cationic derivatives with a controllable degree of substitution. HATU is commonly used in amine acylation reactions.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 148893-10-1
- Formula: C10H15F6N6OP
- Molecular Weight:380.23
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
HATU (0.3-3 eq; 2 h) mediates efficient, controlled N-acylation of chitosan in DMSO, enabling targeted DS values from ~10% to ~86% for TAC and successful one-pot mixed N-acylation with aromatic carboxylic acids, with reaction efficiency optimized via Design of Experiments[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 148893-10-1
-
Appearance Solid
-
Molecular Weight 380.23
-
Formula C10H15F6N6OP
-
Color White to off-white
-
SMILES
F[P-](F)(F)(F)(F)F.C/[N+](C)=C(N(C)C)/ON1C2=NC=CC=C2N=N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (526.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6300 mL | 13.1499 mL | 26.2999 mL | 65.7497 mL |
| 5 mM | 0.5260 mL | 2.6300 mL | 5.2600 mL | 13.1499 mL | |
| 10 mM | 0.2630 mL | 1.3150 mL | 2.6300 mL | 6.5750 mL | |
| 15 mM | 0.1753 mL | 0.8767 mL | 1.7533 mL | 4.3833 mL | |
| 20 mM | 0.1315 mL | 0.6575 mL | 1.3150 mL | 3.2875 mL | |
| 25 mM | 0.1052 mL | 0.5260 mL | 1.0520 mL | 2.6300 mL | |
| 30 mM | 0.0877 mL | 0.4383 mL | 0.8767 mL | 2.1917 mL | |
| 40 mM | 0.0657 mL | 0.3287 mL | 0.6575 mL | 1.6437 mL | |
| 50 mM | 0.0526 mL | 0.2630 mL | 0.5260 mL | 1.3150 mL | |
| 60 mM | 0.0438 mL | 0.2192 mL | 0.4383 mL | 1.0958 mL | |
| 80 mM | 0.0329 mL | 0.1644 mL | 0.3287 mL | 0.8219 mL | |
| 100 mM | 0.0263 mL | 0.1315 mL | 0.2630 mL | 0.6575 mL |
HATU Related Classifications
HY-Y1703 Related Classifications
Powered by Bioz