Bz-rA
Based on 1 Customer Validation
Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway.
For research use only. We do not sell to patients.
- Purity: 99.51%
- CAS No.: 4546-55-8
- Formula: C17H17N5O5
- Molecular Weight:371.35
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RD | CC50 |
>337 μM
Compound: 25
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Cytotoxicity against human RD cells
Cytotoxicity against human RD cells
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[PMID: 26854380] |
| RD | EC50 |
12 μM
Compound: 25
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Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay
Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay
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[PMID: 26854380] |
N6-Benzoyladenosine can react with 1 mM oxidant under irradiation with a 400 W high-pressure mercury lamp, and no cyclization occurs in the absence of oxidant or under thermal conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4546-55-8
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Appearance Solid
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Molecular Weight 371.35
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Formula C17H17N5O5
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Color White to off-white
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SMILES
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O
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Synonyms
N6-Benzoyladenosine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (269.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6929 mL | 13.4644 mL | 26.9288 mL | 67.3219 mL |
| 5 mM | 0.5386 mL | 2.6929 mL | 5.3858 mL | 13.4644 mL | |
| 10 mM | 0.2693 mL | 1.3464 mL | 2.6929 mL | 6.7322 mL | |
| 15 mM | 0.1795 mL | 0.8976 mL | 1.7953 mL | 4.4881 mL | |
| 20 mM | 0.1346 mL | 0.6732 mL | 1.3464 mL | 3.3661 mL | |
| 25 mM | 0.1077 mL | 0.5386 mL | 1.0772 mL | 2.6929 mL | |
| 30 mM | 0.0898 mL | 0.4488 mL | 0.8976 mL | 2.2441 mL | |
| 40 mM | 0.0673 mL | 0.3366 mL | 0.6732 mL | 1.6830 mL | |
| 50 mM | 0.0539 mL | 0.2693 mL | 0.5386 mL | 1.3464 mL | |
| 60 mM | 0.0449 mL | 0.2244 mL | 0.4488 mL | 1.1220 mL | |
| 80 mM | 0.0337 mL | 0.1683 mL | 0.3366 mL | 0.8415 mL | |
| 100 mM | 0.0269 mL | 0.1346 mL | 0.2693 mL | 0.6732 mL |
Bz-rA Related Classifications
HY-W008388 Related Classifications
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