4546-55-8
Chemical Structure
Bz-rA
Synonym(s): N6-Benzoyladenosine
- CAS No.: 4546-55-8
- Formula:C17H17N5O5
- Molecular Weight:371.35
IUPAC Name: N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
InChIKey: NZDWTKFDAUOODA-CNEMSGBDSA-N
SMILES: O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O
Biological Activity: Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway[1][2].
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Bz-rA | 99.51% | Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway. | ||||||||||||||||||||
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- [1]. Shimada K, et al. Oxidative photocyclization of N6-benzoyladenosine derivatives. Facile formation of the quinazolinopurine ring system[J]. Tetrahedron letters, 1987, 28(2): 207-210.
- [2]. Aronoff DM, et al. Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol. 2005 Jan 15;174(2):595-9. [Content Brief]
Keywords
