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Results for "

Ac-Lys(Ac)-D-Ala-D-Ala-OH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Akt (2) Amino Acid Derivatives (2) Amyloid-β (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (9) Apoptosis (5) Bacterial (14) Bcl-2 Family (1) Biochemical Assay Reagents (4) Carboxypeptidase (1) Caspase (3) Cholinesterase (ChE) (1) Complement System (1) Cytochrome P450 (1) Dipeptidyl Peptidase (1) DNA/RNA Synthesis (1) Dopamine Receptor (1) Drug Derivative (1) Drug-Linker Conjugates for ADC (3) Endogenous Metabolite (2) ERK (2) Fluorescent Dye (11) Fungal (4) GABA Receptor (4) GCGR (3) GnRH Receptor (1) Histone Methyltransferase (1) Integrin (1) Liposome (4) MARCKS (1) Mitochondrial Metabolism (2) MMP (5) NF-κB (1) P-selectin (1) PKC (2) STING (1) Thymidylate Synthase (1) Thyroid Hormone Receptor (1) TNF Receptor (1) Topoisomerase (1) Transmembrane Glycoprotein (1) VEGFR (1) β-catenin (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (4) Endocrinology (2) Infection (19) Inflammation/Immunology (13) Metabolic Disease (3) Neurological Disease (7)

By Targets:

ADC Linker (2)

Akt (2)

Amino Acid Derivatives (2)

Amyloid-β (1)

Angiotensin-converting Enzyme (ACE) (1)

Antibiotic (9)

Apoptosis (5)

Bacterial (14)

Bcl-2 Family (1)

Biochemical Assay Reagents (4)

Carboxypeptidase (1)

Caspase (3)

Cholinesterase (ChE) (1)

Complement System (1)

Cytochrome P450 (1)

Dipeptidyl Peptidase (1)

DNA/RNA Synthesis (1)

Dopamine Receptor (1)

Drug Derivative (1)

Drug-Linker Conjugates for ADC (3)

Endogenous Metabolite (2)

ERK (2)

Fluorescent Dye (11)

Fungal (4)

GABA Receptor (4)

GCGR (3)

GnRH Receptor (1)

Histone Methyltransferase (1)

Integrin (1)

Liposome (4)

MARCKS (1)

Mitochondrial Metabolism (2)

MMP (5)

NF-κB (1)

P-selectin (1)

PKC (2)

STING (1)

Thymidylate Synthase (1)

Thyroid Hormone Receptor (1)

TNF Receptor (1)

Topoisomerase (1)

Transmembrane Glycoprotein (1)

VEGFR (1)

β-catenin (1)

By Research Areas:

Cancer (28)

Cardiovascular Disease (4)

Endocrinology (2)

Infection (19)

Inflammation/Immunology (13)

Metabolic Disease (3)

Neurological Disease (7)

Inhibitors & Agonists

Fluorescent Dyes

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4931

Mca-KPLGL-Dap(Dnp)-AR-NH2 1 Publications Verification	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-P1539

Cecropin A 1 Publications Verification	Bacterial Antibiotic	Infection Inflammation/Immunology Cancer
Cecropin A is a linear 37-residue antimicrobial polypeptide, with anticancer and anti-inflammatory activity.

HY-P4322

*H-Ile-Lys-Val-Ala-Val-OH* 1 Publications Verification	ERK Akt	Neurological Disease Cancer
H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways .

HY-P10925A

(Z)-Zolucatetide (Z)-FOG-001; I-67	β-catenin	Cancer
(Z)-Zolucatetide (I-67) is a β-catenin inhibitor with IC₅₀ ≤50 nM. (Z)-Zolucatetide's sequence is Ac-PL3-Asp-Npg-B5-Asp-3COOHF-Aib-Ala-Phe-Lys3-PyrS2-3Thi-BztA-GlnR3-Ala-NH₂. (Z)-Zolucatetide can be used for cancer research .

HY-P0311

LAH4	Bacterial	Infection
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-132828

Odatroltide LT3001; DHDMIQK(KAP)	P-selectin	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Odatroltide (LT3001; DHDMIQK(KAP)) is a P-selectin inhibitor. Odatroltide is a peptide molecule comprising a tripeptide Pro-Ala-Lys (PAK) and an (S)-6,7-dihydroxy-1,1-dimethyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid domain. Odatroltide can restore cerebral blood flow, scavenge free radicals, and inhibit leukocyte migration. Odatroltide possesses thrombolytic and anti-thrombotic activities .

HY-114174

*Fmoc-Ala-Glu-Asn-Lys-NH2* 3 Publications Verification	Amyloid-β	Neurological Disease
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing .

HY-P3749

*Mca-(ala7,lys(dnp)9)-bradykinin*	Fluorescent Dye	Others
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .

HY-P2221

Glepaglutide 1 Publications Verification ZP1848	GCGR	Inflammation/Immunology
Glepaglutide (ZP1848), a long-acting GLP-2 analogue, is a potent GLP-2R agonist. Glepaglutide reduces faecal output and increases intestinal absorption. Glepaglutide alleviates small intestinal inflammation. Glepaglutide can be used in the research of inflammatory bowel disease (IBD) and Crohn’s disease .

HY-P0092

Cecropin B 1 Publications Verification	Cytochrome P450 Bacterial Antibiotic	Infection Cancer
Cecropin B has high level of antimicrobial activity and is considered as a valuable peptide antibiotic.

HY-111956B

*D-Ala-Lys-AMCA hydrochloride* 1 Publications Verification	Fluorescent Dye	Cancer
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .

HY-D1154

*β-Ala-Lys(AMCA)*	Fluorescent Dye	Others
β-Ala-Lys (AMCA) is a fluorescently labeled substrate of oligopeptide transporters . β-Ala-Lys (AMCA) acts as a substrate for a variety of bacterial proton-coupled oligopeptide transporters, and is used to label the activity of oligopeptide transporters. Excitation/emission wavelength: 340 nM/460 nM .

HY-P2536

*Mca-Ala-Pro-Lys(Dnp)-OH* 2 Publications Verification	Angiotensin-converting Enzyme (ACE)	Others
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .

HY-P5189A

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P10551

ApoA-I mimetic peptide 5A	Transmembrane Glycoprotein NF-κB TNF Receptor	Cardiovascular Disease
ApoA-I mimetic peptide 5A is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). ApoA-I mimetic peptide 5A can promote the efflux of cholesterol from cells and help reduce the accumulation of cholesterol in cells. ApoA-I mimetic peptide 5A also shows anti-inflammatory activity and can reduce inflammatory markers in blood and tissues. ApoA-I mimetic peptide 5A can be used in the study of cardiovascular diseases .

HY-P2221B

Glepaglutide acetate 1 Publications Verification ZP1848 acetate	GCGR	Inflammation/Immunology
Glepaglutide (ZP1848) acetate, a long-acting GLP-2 analogue, is a potent GLP-2R agonist. Glepaglutide acetate reduces faecal output and increases intestinal absorption. Glepaglutide acetate alleviates small intestinal inflammation. Glepaglutide acetate can be used in the research of inflammatory bowel disease (IBD) and Crohn’s disease .

HY-P11460

Vectofusin-1	Drug Derivative	Infection
Vectofusin-1 is a histidine-rich cationic amphipathic peptide derived from the LAH4 (HY-P0311) peptide family, and also acts as a Viral entry enhancer. Vectofusin-1 promotes the adhesion and fusion of retroviral/lentiviral vectors with cell membranes during viral entry, thereby improving transduction efficiency. Vectofusin-1 potently enhances lentiviral transduction of cells .

HY-P3726

Lys-Gln-Ala-Gly-Asp-Val	Integrin	Inflammation/Immunology Cancer
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α_2bβ₃ integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) .

HY-P4360

*Suc-Ala-Phe-Lys-AMC*	Fluorescent Dye	Others
Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K .

HY-P5345

KLA peptide	Apoptosis Antibiotic Caspase Mitochondrial Metabolism	Cardiovascular Disease Infection Neurological Disease Metabolic Disease
KLA peptide is a naturally occurring Antibiotic peptide that is nontoxic outside of cells but is toxic when it enters into the interior of targeted cells. KLA peptide can induce cell Apoptosis by disrupting mitochondrial membranes and activating Caspase. MG1-KLA, formed by the coupling of KLA peptide with MG1, can selectively induce apoptosis in pro-inflammatory microglia. KLA peptide can be used for the research of liver fibrosis. KLA peptide can be used for the research of neonatal hypoxic-ischemic encephalopathy.

HY-P4468

Lys-Ala-pNA	Dipeptidyl Peptidase	Others
Lys-Ala-pNA is hydrolytic substrate the of dipeptidyl peptidase (DPP) II with K_m of 0.42 mM .

HY-111956

*D-Ala-Lys-AMCA*	Fluorescent Dye	Cancer
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .

HY-P5380

TNO211 Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2	MMP Fluorescent Dye	Others
TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2) is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 can specifically detect MMP activity (Ex/Em = 340/485 nm) .

HY-P11211A

D2A21 TFA	Bacterial	Infection Cancer
D2A21 TFA is an antimicrobial peptide with significant antimicrobial activity against Pseudomonas and bactericidal effect on burn scabs. D2A21 TFA has antitumor activity and can be used in prostate cancer research .

HY-P2258

Histone H3 (1-34)	Histone Methyltransferase	Others
Histone H3 (1-34) is a peptide derived from human histone isotype 3.1. Histones are the main protein components of eukaryotic chromatin. Histone variants and histone modifications modulate chromatin structure, ensuring the precise operation of cellular processes associated with genomic DNA .

HY-P3586

HKPao Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide	Apoptosis	Cancer
HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles .

HY-P3498

Elsiglutide ZP1846	GCGR	Others
Elsiglutide (ZP1846) is a GLP-2 analogue, an orally active and selective GLP-2 receptor agonist, increases cell proliferation and reduces apoptosis in the intestine. Elsiglutide improves Lapatinib (HY-50898)-induced diarrhoea in rat model .

HY-178145

*Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan (compound 12) is a Drug-Linker Conjugate for ADC. Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan contains the ADC linker (Mc-Lys(PEG12)-Cap-Ala-Ala-PABC) (HY-178146) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan can be used for the development of ADC targeting HER2-positive breast cancer .

HY-P3741

*[Ala9,10, Lys11,12] Glycogen Synthase (1-12)*	PKC	Neurological Disease
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C .

HY-P5023A

*Cyclo(Arg-Ala-Asp-(D-Tyr)-Lys) TFA* c(RADyK) TFA	Biochemical Assay Reagents	Cancer
Cyclo (ARG-ALA-ASP- (D-Tyr) -LYS) (TFA) (C (Radyk) (TFA)) is a control peptide for c(RGDyK) .

HY-145943

*MP-PEG8-Val-Lys-Ala-7-MAD-MDCPT*	Drug-Linker Conjugates for ADC	Inflammation/Immunology Cancer
MP-PEG8-Val-Lys-Ala-7-MAD-MDCPT is a agent-linker conjugate for antibody-drug conjugate (ADC). MP-PEG8-Val-Lys-Ala-7-MAD-MDCPT has the potential for cancer and autoimmune disease research.

HY-P11211

D2A21	Antibiotic Bacterial	Infection
D2A21, a cecropin peptide, demonstrates a minimum cidal concentration of 21.69 μg/mL against Chlamydia trachomatis .

HY-P11208C

mNLS-CPP-WSTF TFA	GABA Receptor	Inflammation/Immunology
mNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF (HY-P11208). mNLS-CPP-WSTF is a nuclear localization signal (NLS)-cell-penetrating peptide based on the mouse WSTF sequence. mNLS-CPP-WSTF significantly inhibits the GABARAP-WSTF interaction, WSTF degradation and inflammatory gene expression. mNLS-CPP-WSTF effectively attenuates chronic inflammation, liver fibrosis and cartilage damage in metabolic-dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA) mice model. mNLS-CPP-WSTF is promising for research of chronic inflammatory diseases such as MASH and OA .

HY-P0274

PGLa	Bacterial Antibiotic	Infection
PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .

HY-P11455A

Lipopeptide CPE4 TFA	Liposome	Others
Lipopeptide CPE4 TFA is a PEG-modified peptide E4 [(EIAALEK) ⁴]. Lipopeptide CPE4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 TFA can be used for drug delivery research .

HY-P10078

pTH (39-84) (human)	Thyroid Hormone Receptor Apoptosis	Endocrinology
pTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH). pTH (39-84) (human) increases Apoptosis. pTH (39-84) (human) can stimulate osteoclast formation .

HY-178146

*Mc-Lys(PEG12)-Cap-Ala-Ala-PABC*	ADC Linker	Cancer
Mc-Lys(PEG12)-Cap-Ala-Ala-PABC is a linker of MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (HY-178146) .

HY-158348

*m-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag*	Drug-Linker Conjugates for ADC STING	Cancer
m-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag is a drug-linker conjugate for ADC.

HY-P5380A

TNO211 TFA Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 TFA	MMP Fluorescent Dye	Cancer
TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2) TFA is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 TFA can specifically detect MMP activity (Ex/Em = 340/485 nm) .

HY-P4144

Onvitrelin ucalontide Phor18-LHRH (338613); EP-100	GnRH Receptor	Endocrinology Cancer
Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model .

HY-P10997

F3 peptide	DNA/RNA Synthesis	Cancer
F3 peptide is a fragment of the human high mobility group protein 2 (HMGB2), and can specifically bind to nucleolin expressed on the membrane of cancer cells, neovasculature, and endothelium. F3 peptide can be used as an effective ligand to improve their druggability of macromolecular drugs or nanoparticles, and so on .

HY-P11208B

mNLS-CPP-scramble TFA	GABA Receptor	Inflammation/Immunology
mNLS-CPP-scramble (TFA) is the trifluoroacetate salt of mNLS-CPP-scramble (HY-P11208A). mNLS-CPP-scramble is a negative control peptide of mNLS-CPP-WSTF. mNLS-CPP-scramble is promising for research of chronic inflammatory diseases (e.g., MASH, osteoarthritis) .

HY-P11208A

mNLS-CPP-scramble	GABA Receptor	Inflammation/Immunology
mNLS-CPP-scramble is a negative control peptide of mNLS-CPP-WSTF. mNLS-CPP-scramble is promising for research of chronic inflammatory diseases (e.g., MASH, osteoarthritis) .

HY-P11208

mNLS-CPP-WSTF	GABA Receptor	Inflammation/Immunology
mNLS-CPP-WSTF is a nuclear localization signal (NLS)-cell-penetrating peptide based on the mouse WSTF sequence. mNLS-CPP-WSTF significantly inhibits the GABARAP-WSTF interaction, WSTF degradation and inflammatory gene expression. mNLS-CPP-WSTF effectively attenuates chronic inflammation, liver fibrosis and cartilage damage in metabolic-dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA) mice model. mNLS-CPP-WSTF is promising for research of chronic inflammatory diseases such as MASH and OA .

HY-P1444

Acein	Dopamine Receptor	Neurological Disease
Acein is a novel nonapeptide, H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Acein can promote the release of dopamine. Acein targets angiotensin converting enzyme (ACE I). Angiotensin converting enzyme (ACE I) can be used in nervous system related research .

HY-P3729

*Ac-Lys-D-Ala-D-Ala-OH*	Biochemical Assay Reagents	Others
Ac-Lys-D-Ala-D-Ala-OH is an oligopeptide. Ac-Lys-D-Ala-D-Ala-OH can be used for the research of various biochemical .

HY-P4339

Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Ala-Phe-Lys-AMC is a fluorogenic substrate, which can be used for residual plasmin activity assay .

HY-P4347

*MeOSuc-Ala-Phe-Lys-AMC TFA*	Amino Acid Derivatives	Others
MeOSuc-Ala-Phe-Lys-AMC TFA is a peptide substrate of plasmin .

HY-P3882

*Fmoc-Ala-Glu-Gln-Lys-NH2*	Amino Acid Derivatives	Neurological Disease
Fmoc-Ala-Glu-Gln-Lys-NH2 (AEQK) is a tetrapeptide. Fmoc-Ala-Glu-Gln-Lys-NH2 is the inactive control for Fmoc-Ala-Glu-Asn-Lys-NH2 (AENK) peptide inhibitor. AENK blocks proteolysis of UNC5C protein .

HY-111956A

*D-Ala-Lys-AMCA TFA*	Fluorescent Dye	Cancer
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .

Cat. No.	Product Name	Type