HKPao
Based on 1 Customer Validation
HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles.
For research use only. We do not sell to patients.
- Purity: 95.11%
- CAS No.: 859216-15-2
- Formula: C111H206N36O28S2
- Molecular Weight:2557.18
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
HKPao can induce leakage of fluorescent dextrans from vesicles that have a larger hydrodyanmic radius[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 859216-15-2
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Appearance Solid
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Molecular Weight 2557.18
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Formula C111H206N36O28S2
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Color White to off-white
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Synonyms
Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide
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Sequence
Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys-Gly-Gly-d(Lys-Leu-Ala-Lys-Leu-Ala-Lys-Lys-Leu-Ala-Lys-Leu-Ala-Lys)
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Sequence Shortening
CKGGRAKDCGG-d(KLAKLAKKLAKLAK)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (258 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Cristina M Sandoval, et al. Anti-obesity and anti-tumor pro-apoptotic peptides are sufficient to cause Cristina M Sandoval, et al. Anti-obesity and anti-tumor pro-apoptotic peptides are sufficient to cause release of cytochrome c from vesicles. FEBS Lett. 2007 Nov 27;581(28):5464-8.release of cytochrome c from vesicles. FEBS Lett. 2007 Nov 27;581(28):5464-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)