F3 peptide
F3 peptide is a fragment of the human high mobility group protein 2 (HMGB2), and can specifically bind to nucleolin expressed on the membrane of cancer cells, neovasculature, and endothelium. F3 peptide can be used as an effective ligand to improve their druggability of macromolecular drugs or nanoparticles, and so on.
For research use only. We do not sell to patients.
- CAS No.: 536971-53-6
- Formula: C152H263N49O41
- Molecular Weight:3433.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 536971-53-6
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Molecular Weight 3433.02
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Formula C152H263N49O41
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Sequence
Lys-Asp-Glu-Pro-Gln-Arg-Arg-Ser-Ala-Arg-Leu-Ser-Ala-Lys-Pro-Ala-Pro-Pro-Lys-Pro-Glu-Pro-Lys-Pro-Lys-Lys-Ala-Pro-Ala-Lys-Lys
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Sequence Shortening
KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hu Q, et al. F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery. Biomaterials. 2013 Jan;34(4):1135-45. [Content Brief]
[2]. Ham SH, et al. Molecular tumor targeting of gelonin by fusion with F3 peptide. Acta Pharmacol Sin. 2017 Jun;38(6):897-906. [Content Brief]
[3]. Tao Z, et al. Multivalent assembly of nucleolin-targeted F3 peptide potentiates TRAIL's tumor penetration and antitumor effects. J Control Release. 2025 Jul 10;383:113835. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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