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  3. D-Ala-Lys-AMCA

D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors.

For research use only. We do not sell to patients.

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D-Ala-Lys-AMCA Chemical Structure

D-Ala-Lys-AMCA Chemical Structure

CAS No. : 375822-19-8

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Description

D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors[1][2].

In Vitro

D-Ala-Lys-AMCA (25, 50 and 150 μM, 3 h) may be transported into liver cancer and Caco-2 cells[1].
D-Ala-Lys-AMCA (25 μM, 10 min) can be uptaken by absorptive enterocytes of all small intestine segments, whereas there is a complete lack of fluorescence in colonic samples[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

432.47

Formula

C21H28N4O6

CAS No.
Emission (Em)

480

Excitation (Ex)

390

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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D-Ala-Lys-AMCA Related Classifications

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D-Ala-Lys-AMCA
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HY-111956
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