Suc-Ala-Phe-Lys-AMC

Cat. No.: HY-P4360 Purity: 99.86%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Suc-Ala-Phe-Lys-AMC Chemical Structure

CAS No. : 73207-91-7

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K^[1]^[2].

IC₅₀ & Target

others

Molecular Weight

621.68

Formula

C₃₂H₃₉N₅O₈

CAS No.

73207-91-7

Appearance

Solid

Color

White to off-white

Sequence

{Suc-Ala}-Phe-{Lys-AMC}

Sequence Shortening

{Suc-Ala}-F-{Lys-AMC}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (160.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6085 mL	8.0427 mL	16.0854 mL
5 mM	0.3217 mL	1.6085 mL	3.2171 mL
10 mM	0.1609 mL	0.8043 mL	1.6085 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.86%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (246 KB) RP-HPLC (204 KB)

Handling Instructions (2659 KB)

References

[1]. P A Pierzchala, et al. A new fluorogenic substrate for plasmin. Biochem J. 1979 Dec 1;183(3):555-9. [Content Brief]

[2]. Marion G Götz, et al. Aza-peptidyl Michael Acceptors. A New Class of Potent and Selective Inhibitors of Asparaginyl Endopeptidases (Legumains) from Evolutionarily Diverse Pathogens. J Med Chem. 2008 May 8;51(9):2816-32. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6085 mL	8.0427 mL	16.0854 mL	40.2136 mL
	5 mM	0.3217 mL	1.6085 mL	3.2171 mL	8.0427 mL
	10 mM	0.1609 mL	0.8043 mL	1.6085 mL	4.0214 mL
	15 mM	0.1072 mL	0.5362 mL	1.0724 mL	2.6809 mL
	20 mM	0.0804 mL	0.4021 mL	0.8043 mL	2.0107 mL
	25 mM	0.0643 mL	0.3217 mL	0.6434 mL	1.6085 mL
	30 mM	0.0536 mL	0.2681 mL	0.5362 mL	1.3405 mL
	40 mM	0.0402 mL	0.2011 mL	0.4021 mL	1.0053 mL
	50 mM	0.0322 mL	0.1609 mL	0.3217 mL	0.8043 mL
	60 mM	0.0268 mL	0.1340 mL	0.2681 mL	0.6702 mL
	80 mM	0.0201 mL	0.1005 mL	0.2011 mL	0.5027 mL
	100 mM	0.0161 mL	0.0804 mL	0.1609 mL	0.4021 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Suc-Ala-Phe-Lys-AMC73207-91-7OthersPlasmin/Gingipain K SubstrateInhibitorinhibitorinhibit

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Suc-Ala-Phe-Lys-AMC

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