TNO211
Based on 1 Customer Validation
TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2) is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 can specifically detect MMP activity (Ex/Em = 340/485 nm).
For research use only. We do not sell to patients.
- Purity: 99.41%
- CAS No.: 193475-71-7
- Formula: C63H88N16O14S
- Molecular Weight:1325.54
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 193475-71-7
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Appearance Solid
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Molecular Weight 1325.54
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Formula C63H88N16O14S
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Color Yellow to orange
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Synonyms
Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2
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Sequence
{DABCYL-GABA}-Pro-Gln-Gly-Leu-Glu-{EDANS}-Ala-Lys-NH2
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Sequence Shortening
{DABCYL-GABA}-PQGL-{Glu(EDANS)}-AK-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (75.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7544 mL | 3.7720 mL | 7.5441 mL | 18.8602 mL |
| 5 mM | 0.1509 mL | 0.7544 mL | 1.5088 mL | 3.7720 mL | |
| 10 mM | 0.0754 mL | 0.3772 mL | 0.7544 mL | 1.8860 mL | |
| 15 mM | 0.0503 mL | 0.2515 mL | 0.5029 mL | 1.2573 mL | |
| 20 mM | 0.0377 mL | 0.1886 mL | 0.3772 mL | 0.9430 mL | |
| 25 mM | 0.0302 mL | 0.1509 mL | 0.3018 mL | 0.7544 mL | |
| 30 mM | 0.0251 mL | 0.1257 mL | 0.2515 mL | 0.6287 mL | |
| 40 mM | 0.0189 mL | 0.0943 mL | 0.1886 mL | 0.4715 mL | |
| 50 mM | 0.0151 mL | 0.0754 mL | 0.1509 mL | 0.3772 mL | |
| 60 mM | 0.0126 mL | 0.0629 mL | 0.1257 mL | 0.3143 mL |
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