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Odatroltide (Synonyms: DHDMIQK(KAP))

Cat. No.: HY-132828
Handling Instructions

Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus.

For research use only. We do not sell to patients.

Odatroltide Chemical Structure

Odatroltide Chemical Structure

CAS No. : 1639303-73-3

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Description

Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus[1].

IC50 & Target

P-selectin[1]

In Vitro

Odatroltide (1 nM) effectively down-regulates P-selectin expression. DHDMIQK(KAP) effectively inhibits platelet aggregation via down-regulating the expression of P-selectin. Odatroltide effectively inhibits platelet aggregations induced by TH, AA, ADP and PAF, which are correlated with the downregulation of P-selectin expression and with the scavenging of the free radicals[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Odatroltide (0.01 nmol/kg) lyses the thrombus and inhibits thrombosis with a minimal[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

661.79

Formula

C₃₂H₅₁N₇O₈

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Odatroltide
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