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Results for "

Drug delivery carrier

" in MedChemExpress (MCE) Product Catalog:

79

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1

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2

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55

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1

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29

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2247A
    PLGA (75:25)
    Maximum Cited Publications
    6 Publications Verification

    poly(lactic-co-glycolic acid) (75:25)

    Biochemical Assay Reagents Others
    PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
    PLGA (75:25)
  • HY-112624B

    Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)

    Bacterial Others
    Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
    Dextran T70 (MW 70,000)
  • HY-D1063
    IR-780
    5+ Cited Publications

    Fluorescent Dye Apoptosis Reactive Oxygen Species (ROS) Cancer
    IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
    IR-780
  • HY-128754
    Monoolein
    1 Publications Verification

    Environmental Pollutants Endogenous Metabolite NO Synthase Interleukin Related TNF Receptor Inflammation/Immunology
    Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .
    Monoolein
  • HY-113011
    Maltotriose
    1 Publications Verification

    Endogenous Metabolite Others
    Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer .
    Maltotriose
  • HY-W127512
    5β-Cholanic acid
    1 Publications Verification

    Drug Intermediate Others
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
    5β-Cholanic acid
  • HY-W583868

    1,2-POPE; 16:0-18:1 PE

    Liposome Others
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PE
  • HY-W068119A

    2-Maleimidoethylamine hydrochloride

    Biochemical Assay Reagents Cancer
    N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a selective covalent binding agent for thiol groups (RSGs), covalently binding to thiols via an irreversible thioether bond to prepare MMP-2-sensitive nanosystems. Under near-neutral conditions, the maleimide group in N-(2-Aminoethyl)maleimide hydrochloride binds to thiol groups via a nucleophilic addition reaction, and can be used to modify polymers or biological interfaces, enhancing mucosal adhesion and regulating the surface charge of biological interfaces. N-(2-Aminoethyl)maleimide hydrochloride can optimize the adhesion performance of drug delivery carriers and cell interactions with biological interfaces, and is applied in transmucosal drug delivery systems (such as drug carriers for oral and bladder sites) and biomaterial surface engineering research, providing support for tissue implantation, regeneration, and related drug delivery .
    N-(2-Aminoethyl)maleimide hydrochloride
  • HY-112760
    18:0 mPEG2000 PE sodium
    1 Publications Verification

    DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium

    Liposome Others
    18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
    18:0 mPEG2000 PE sodium
  • HY-W250313

    PLA

    Biochemical Assay Reagents Others Cancer
    Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds .
    Polylactic acid
  • HY-W075517

    2-Methylimidazole zinc salt

    Caspase Pyroptosis MOFs Cancer
    ZIF-8 (2-Methylimidazole zinc salt) is a caspase-1/Gasdermin D activator and a pH- and stimulus-responsive inducer of drug release, which serves as a highly efficient drug delivery carrier. ZIF-8 is a metal-organic framework (MOF). ZIF-8 activates the caspase-1/Gasdermin D-dependent pyroptosis pathway, induces pyroptosis, necrosis and immunogenic cell death, initiates in situ anti-tumor immunity, reprograms the immunosuppressive tumor microenvironment and inhibits tumor proliferation. ZIF-8 is applicable to related research on multiple cancers including colorectal cancer and breast cancer .
    ZIF-8
  • HY-P10709

    Collagen Cardiovascular Disease Cancer
    CREKA peptide is a selective non-covalent binding agent targeting fibrin, type IV collagen, and fibronectin, often used as a targeting ligand to modify delivery carriers. CREKA peptide specifically recognizes fibrin, fibronectin, and type IV collagen that are excessively deposited in the tumor microenvironment or fibrotic tissue, mediating the targeted accumulation of the carrier at the lesion site and promoting drug internalization into target cells (such as cancer cells and activated hepatic stellate cells). CREKA peptide can enhance targeted delivery efficiency, increase drug concentration at the lesion site, and reduce systemic side effects .
    CREKA peptide
  • HY-D1005A2

    PEG-PPG-PEG, 1900 (Average)

    Environmental Pollutants Biochemical Assay Reagents Others
    Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
    Poloxamer 105 (L35)
  • HY-112624J

    Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)

    Bacterial Others
    Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
    Dextran T4 (MW 4,000)
  • HY-W250721A

    CBM 940

    Biochemical Assay Reagents Others
    Carbomer 940 (CBM 940) is an acrylic polymer with high viscosity, good thermal stability and histocompatibility. Carbomer 940 serves as a transdermal drug delivery carrier and an external gel matrix. Carbomer 940 has no cytotoxicity, and it can also improve blood supply in the stasis zone of burns and promote wound repair. Carbomer 940 is applicable to pharmaceutical research .
    Carbomer 940
  • HY-155882

    mPEG750-NH2

    Biochemical Assay Reagents Cancer
    mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .
    mPEG750-amine
  • HY-112624I

    Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)

    Bacterial Others
    Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
    Dextran T3 (MW 3,000)
  • HY-D1005A10

    PEG-PPG-PEG, 2900 (Average)

    Environmental Pollutants Biochemical Assay Reagents Bacterial P-glycoprotein Infection Inflammation/Immunology
    Poloxamer 184 L64 is a block copolymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 2900. Poloxamer has the ability to inhibit P-gp. Poloxamer 184 exhibits short-term skin toxicity, characterized by mild erythema and intradermal inflammatory reactions. Poloxamer 184 has antimicrobial activity, inhibiting 60% of Mycobacterium avium at a concentration of 1 mg/mL. Poloxamer 184 forms a thermoreversible hydrogel and is used as a food additive and as a drug delivery carrier in cosmetics and tissue engineering .
    Poloxamer 184 (L64)
  • HY-B0633D

    CD44 Endogenous Metabolite Bacterial Akt PI3K Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units, with a molecular weight of 200-1560. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid sodium exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid sodium activates PI3K-Akt signaling. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid sodium is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid sodium can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid sodium can lubricate the corneal endothelium. Hyaluronic acid sodium can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid sodium has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid sodium can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
    Hyaluronic acid sodium (MW 200-1560)
  • HY-B0633E

    Hyaluronan, low endotoxin; Hyaluronate, low endotoxin

    Endogenous Metabolite CD44 Bacterial Akt PI3K Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
    Hyaluronic acid, low endotoxin
  • HY-P10128
    GE11
    1 Publications Verification

    Biochemical Assay Reagents Inflammation/Immunology
    GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .
    GE11
  • HY-Y0873O

    Polyethylene glycol 35000

    Environmental Pollutants Biochemical Assay Reagents Others
    PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .
    PEG35000
  • HY-B0633B

    Hyaluronan (MW 50000-100000); Hyaluronate (MW 50000-100000)

    Biochemical Assay Reagents PI3K Others
    Hyaluronic acid (MW 50000-100000) (Hyaluronan (MW 50000-100000)) is a biopolymer composed of repeating units of disaccharides with a molecular weight of 50000-100000 Da. Hyaluronic acid (MW 50000-100000) can be used as a drug carrier for drug delivery .
    Hyaluronic acid (MW 50000-100000)
  • HY-172470

    Liposome EGFR Cancer
    DSPE-PEG2000-GE11 is a nanocarrier component composed of DSPE and the EGFR-targeting peptide (GE11). DSPE-PEG2000-GE11 specifically binds to EGFR and mediates receptor-mediated endocytosis of micellar drug carriers. DSPE-PEG2000-GE11 can be used for drug delivery .
    DSPE-PEG2000-GE11
  • HY-112624K

    Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)

    Apoptosis Autophagy Others
    Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
    Dextran T5 (MW 5,000)
  • HY-P10502

    LDLR Infection
    L57 is a low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 exhibits high affinity for LRP1, with an EC50 of 45 nM. L57 possesses blood-brain barrier (BBB) permeability and plasma stability. L57 can serve as a carrier for central nervous system drug delivery .
    L57
  • HY-112624E

    Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)

    Biochemical Assay Reagents Others
    Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
    Dextran T0.8 (MW 800)
  • HY-112624H

    Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)

    Biochemical Assay Reagents Others
    Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .
    Dextran T2 (MW 2,000)
  • HY-N5139
    Lecithins, egg
    1 Publications Verification

    Lecithins, egg yolk; Belovo PL 85

    Cholinesterase (ChE) Angiotensin-converting Enzyme (ACE) Bacterial Infection Neurological Disease Metabolic Disease Inflammation/Immunology
    Lecithins, egg (Lecithins, egg yolk; Belovo PL 85) is an orally active natural phospholipid mixture extracted from egg yolks . Lecithins, egg inhibits the activities of acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE). Lecithins, egg exhibits antibacterial, antioxidant and anti-inflammatory activities, and helps delay cellular senescence. Lecithins, egg enhances nerve conduction, improves memory and cognitive function, and exerts positive effects on delaying neurodegenerative diseases. Lecithins, egg promotes lipid absorption and alleviates diarrhea. Lecithins, egg acts as a high-efficiency drug carrier for the preparation of targeted drug delivery systems such as liposomes .
    Lecithins, egg
  • HY-142997

    Liposome Cancer
    DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery .
    DOSPA
  • HY-W440917

    Liposome Others
    DSPE-PEG5000-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
    DSPE-PEG5000-FITC
  • HY-W145493

    Tetraglycol; Poly(ethylene glycol) tetrahydrofurfuryl ether

    Biochemical Assay Reagents Others
    Glycofurol (Tetraglycol) is a hydrophilic, water-miscible cosolvent and absorption enhancer with skin tolerance. Glycofurol can be used as a carrier-based gel for the topical delivery of drugs, including water-insoluble drugs. Glycofurol can form gels with bioadhesiveness, spreadability and suitable viscosity for topical administration .
    Glycofurol
  • HY-142980

    Dioleoylphosphatidylglycerol

    Liposome Inflammation/Immunology
    DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .
    DOPG
  • HY-W440916

    Liposome Others
    DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
    DSPE-PEG3400-FITC
  • HY-P10502A

    LDLR Others
    L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 acetate exhibits high affinity to LRP1 with Ki of 45 nM. L57 acetate exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 acetate can be utilized as the carrier for CNS drug delivery .
    L57 acetate
  • HY-W250121

    Environmental Pollutants Biochemical Assay Reagents Infection Inflammation/Immunology Cancer
    Tragacanth gum is an orally active anionic composite polysaccharide and multifunctional biomaterial. Tragacanth gum exhibits biocompatibility, mucoadhesion and renoprotective effects, and effectively promotes wound closure and tissue healing. Tragacanth gum can be isolated from Astragalus gummifer. Tragacanth gum acts as an emulsifier and drug delivery carrier, and is also widely used in fields such as 3D scaffolds, tissue engineering and green nanoparticle preparation. High doses of Tragacanth gum may induce reversible forestomach squamous epithelial hyperplasia in mice, but show no mutagenic or carcinogenic activity. Tragacanth gum is commonly used in studies related to diseases including systemic candidiasis, rheumatoid arthritis and osteosarcoma .
    Tragacanth gum
  • HY-W441009A

    Liposome Others
    DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
    DSPE-PEG3400-Maleimide ammonium
  • HY-P4123

    MMP Cardiovascular Disease Inflammation/Immunology Cancer
    TAT (47-57) GGG-Cys (Npys) is a cell-penetrating peptide and delivery carrier derived from TAT. TAT (47-57) GGG-Cys (Npys) facilitates the translocation of conjugated drug molecules across cell membranes. TAT (47-57) GGG-Cys (Npys) acts as a delivery carrier for MT1-MMP inhibitors. TAT (47-57) GGG-Cys (Npys) is applicable to research on diseases associated with MT1-MMP activity, such as cancer, arthritis, heart disease, and vascular disorders .
    TAT (47-57) GGG-Cys(Npys)
  • HY-144027

    Biochemical Assay Reagents Others
    Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .
    Dolichol (13~21)
  • HY-W441009B

    Liposome Others
    DSPE-PEG1000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG1000-Maleimide ammonium can be used in drug delivery research .
    DSPE-PEG1000-Maleimide ammonium
  • HY-D1005A4

    PEG-PPG-PEG, 1630 (Average)

    Biochemical Assay Reagents Infection
    Poloxamer 122 L42 (PEG-PPG-PEG, 1630 (Average)) is a synthetic nonionic triblock copolymer composed of polyoxyethylene-polyoxypropylene, with emulsifying and wetting properties. Poloxamer 122 L42 forms large spherical aggregates in aqueous solutions near its cloud point,. Poloxamer 122 L42 can form thermoreversible hydrogels, and is also used in research related to serving as a drug delivery carrier in the fields of food additives, cosmetics, pharmaceutical preparations and tissue engineering .
    Poloxamer 122 (L42)
  • HY-D1005A7

    PEG-PPG-PEG, 2400 (Average)

    Biochemical Assay Reagents Others
    Poloxamer 125 (L45) (PEG-PPG-PEG, 2400 (Average)) is a block polymer of polyoxyethylene and polyoxypropylene, belonging to water-soluble non-ionic biosurfactants with properties such as emulsification and wetting. Poloxamer 125 (L45) has thermosensitive characteristics and can form thermoreversible hydrogels in aqueous solutions, presenting a fluid state at room temperature and transforming into a viscous gel under body temperature conditions; when its concentration is higher than the critical micelle concentration, it can also self-assemble into micelles in aqueous systems. Poloxamer 125 (L45) enables controlled drug release, prolongs the local retention time of drugs, and is often used as a drug delivery carrier. Poloxamer 125 (L45) can be applied in the fields of cosmetics, biomedicine and tissue engineering .
    Poloxamer 125 (L45)
  • HY-164657

    PAMAM

    Radionuclide-Drug Conjugates (RDCs) Cancer
    Polyamidoamine (PAMAM) (20% in methanol) is a new type of drug carrier that has drug encapsulation capabilities internally and biocompatibility on the surface, and can be used as a drug delivery system.
    Polyamidoamine (20% in methanol)
  • HY-W1123933B

    CLS-PEG1000-CLS

    Biochemical Assay Reagents Others
    Cholesterol-PEG1000-Cholesterol (CLS-PEG1000-CLS) is a cholesterol-modified PEG derivative. Cholesterol-PEG1000-Cholesterol can be combined with liposomes to form nanolipid carriers for drug delivery .
    Cholesterol-PEG1000-Cholesterol
  • HY-W1113135

    Biochemical Assay Reagents Others
    Carboxymethyl-β-cyclodextrin sodium salt is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
    Carboxymethyl-β-cyclodextrin sodium salt
  • HY-158255

    Biochemical Assay Reagents Others
    mPEG-PLGA (2000-80000) (LA/GA 50:50) is a copolymer, which consists of hydrophilic mPEG and biodegradable PLGA (molar ratio is 50:50) with a molecular weight of 2000 (mPEG) + 80000 (PLGA). mPEG-PLGA (2000-80000) (LA/GA 50:50) forms nanoparticles or microparticles, which is stable in aqueous solution at different pH values and elevated temperatures as well as in serum. mPEG-PLGA (2000-80000) (LA/GA 50:50) is utilized as carrier material in drug delivery systems .
    mPEG-PLGA (2000-80000) (LA/GA 50:50)
  • HY-158220C

    HAMA (MW 50000)

    Biochemical Assay Reagents Others
    Hyaluronic acid methacryloyl (HAMA) (MW 50000) is a methacrylate-modified hyaluronic acid that serves as a hydrogel former, hydrolysis-resistant material, photocrosslinkable hydrogel scaffold, and drug delivery carrier for tissue engineering. Hyaluronic acid methacryloyl (MW 50000) forms hydrogels via photocrosslinking; when combined with AuMA NPs through a one-step photocrosslinking method, its effective swelling ratio increases, and the mechanical reinforcement effect of Au NPs compensates for the impact caused by reduced crosslinking density. Hyaluronic acid methacryloyl (MW 50000) can be combined with AuMA NPs via a one-step photocrosslinking method, enabling non-invasive monitoring of hydrogel degradation with contrast-enhanced micro-CT .
    Hyaluronic acid methacryloyl (MW 50000)
  • HY-144008

    Liposome Others
    C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
    C8 PEG-Ceramide
  • HY-158209

    Biochemical Assay Reagents Others
    Block polyoxyethylene-polyoxypropylene is a block copolymer composed of hydrophilic polyoxyethylene (POE) and hydrophobic polyoxypropylene (POP), which can be used to prepare biological materials such as emulsifiers, drug delivery carriers, and stabilizers .
    Block polyoxyethylene-polyoxypropylene
  • HY-W160127

    N-Methylolsuccinimide

    Biochemical Assay Reagents Others
    N-Hydroxymethyl succinimide (N-Methylolsuccinimide) is a promoiety used as a prodrug carrier for non-steroidal anti-inflammatory drugs (NSAIDs). N-Hydroxymethyl succinimide enhances the lipophilicity of NSAIDs and reducing the gastrointestinal toxicity of NSAIDs. N-Hydroxymethyl succinimide is promising for research of anti-inflammatory drug delivery system .
    N-Hydroxymethyl succinimide

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